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MetabolomicsIntegrated multi-omics of feces, plasm aand urine can describe and differentiate pediatric active Crohn’s Disease from remission

Background

This study aimed to obtain a holistic view of remission in pediatric Crohn’s Disease (CD) by integrating six omics datasets from three anatomical compartments.


Methods

Patients with fecal calprotectin below 250 mg/kg were c...

2025-07-09 | MTBLS9877 | MetaboLights
MetabolomicsIntegrated microbiome and metabolome analysis of milk of lactational mastitis women in remission period
Lactational mastitis is a disease that brings pain to mothers and interrupts breastfeeding. After remission, mothers and doctors care about whether the milk is suitable to continue breastfeeding or not. However, relevant research, particularly multi-omics studies focusing on the remission phase of l...
2026-04-01 | MTBLS14200 | MetaboLights
TranscriptomicsRemission in Polyarticular Juvenile Idiopathic Arthritis
Identify biomarkers to predict response to therapy in polyarticular juvenile idiopathic arthritis (JIA) using gene expression microarrays. 42 samples from 13 controls, 14 active patients, 9 patients in clinical remission with medication (CRM), and 6 patients in clinical remission without medication ...
ORGANISM(S): Homo sapiens 
2009-04-13 | E-GEOD-15645 | biostudies-arrayexpress
TranscriptomicsMolecular basis for remission and tolerance induction in pediatric ITP
Children with newly diagnosed ITP that after 12 month enter remission, shows molecular separate entities. The molecular basis for remission and tolerance induction is characterized by gene transcriptional profiling Global gene expression profile in isolated T-cells from 6 children with newly diagnos...
ORGANISM(S): Homo sapiens 
2016-02-06 | E-GEOD-56232 | biostudies-arrayexpress
ProteomicsPlasma proteomics in children with new-onset type 1 diabetes: a strong tool to identify partial remission biomarkers
Partial remission (PR) occurs in only half of patients with new-onset type 1 diabetes (T1D) and correspond to a transient period characterized by low daily insulin needs, low glycemic fluctuations and increased endogenous insulin secretion. While identification of newly-onset T1D patients with signi...
ORGANISM(S): Homo sapiens (Human) 
2024-04-05 | PXD049795 | Pride
Plasma proteomics Remission Biomarkers Type 1 diabetes 
TranscriptomicsSNP arrays in matched diagnosis/remission samples of normal karyotype-acute myeloid leukemia
We analysed, by last-generation high-resolution SNP arrays, Normal Karyotype (NK)-AML patients at diagnosis (Dx) and remission (R) phases, in order to determine the number of tumor-associated copy number abnormalities (CNAs) and copy neutral-loss of heterozygosity (CN-LOH) regions per patient and to...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-21780 | biostudies-arrayexpress
TranscriptomicsMuscle - atypical diabetes protein expression
Skeletal muscle biopsies from atypical diabetics at presentation and remission. Protein expression determined with antibody arrays
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-634 | biostudies-arrayexpress
TranscriptomicsEvaluation of transcriptomic profiles of peripheral blood myeloid cell subsets of RA patients in remission prior to cDMARD withdrawal, and at the point of flare / 6 months after in sustained remission
To test the contribution of distinct ST-DC populations to either autoimmunity and inflammation or sustained disease remission, we evaluated the phenotypes of their blood precursors in a human model of disease flare following treatment withdrawal in RA patients in disease remission (the BioRRA study,...
ORGANISM(S): Homo sapiens 
2024-12-09 | E-MTAB-14169 | biostudies-arrayexpress
ModelsChakrabarty2010 - A control theory approach to cancer remission aided by an optimal therapy
This is a reinvestigation of a previous model depicting cancer remission. It involves application of mathematical tools from control theory to assess the optimal approach during the use of Adaptive Cellular Immunotherapy and interleukin-2 treatment.
2024-09-02 | BIOMD0000000777 | BioModels
Immuno-oncology 
TranscriptomicsSingle cell RNA and CITE sequencing of cells from synovial tissue biopsies of healthy donors, and Rheumatoid Arthritis (RA) patients with active disease or sustained clinical remission
The dataset includes the raw FASTQ files generated from the 10x Genomics Single Cell 3’ v3.1 experiments. For samples processed with TotalSeq Hashtag reagents, the corresponding hashtag oligonucleotide and condition annotations are provided as separate .csv files. The processed matrices contain filt...
ORGANISM(S): Homo sapiens 
2024-12-06 | E-MTAB-14213 | biostudies-arrayexpress
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