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MetabolomicsUntargeted Metabolomics Reveals a Mild Impact of Remote Ischemic Conditioning on the Plasma Metabolome and α-Hydroxybutyrate as a Possible Cardioprotective Factor and Biomarker of Tissue Ischemia
Remote ischemic conditioning (RIC) is a maneuver by which short non-lethal ischemic events are applied on distant organs or limbs to reduce ischemia and reperfusion injuries caused by e.g. heart attacks. As RIC can be induced using a simple blood pressure cuff e.g. prior to revascularization, it con...
2016-12-20 | MTBLS414 | MetaboLights
TranscriptomicsRemote ischemic preconditioning in on-pump coronary artery bypass graft surgery
In this placebo-controlled randomized controlled trial, we tested whether remote ischemic preconditioning (RIPC) elicited by four 5-minute cycles of 300 mmHg of cuff inflation/deflation of the lower limb would reduce myocardial necrosis in isoflurane-anesthetized patients undergoing on-pump coronary...
ORGANISM(S): Homo sapiens 
2012-10-12 | E-GEOD-29396 | biostudies-arrayexpress
TranscriptomicsGene expression changes in the periventricular white matter of neonatal piglets at a defined 48h time point following a hypoxic-ischemic insult: a comparison of piglets left untreated and those treated with a remote post-conditioning stimulus applied to the hind leg immediately after the insult.
Remote ischemic postconditioning (RIPostC) is a promising therapeutic intervention whereby brief episodes of ischemia/reperfusion of one organ (limb) mitigate damage in another organ (brain) that has experienced severe hypoxia-ischemia. 16 Large White newborn female piglets were exposed to a tightl...
ORGANISM(S): Sus scrofa 
2016-09-21 | E-MTAB-5125 | biostudies-arrayexpress
ProteomicsProteomic analysis identifies plasma correlates of remote ischemic conditioning in the context of experimental traumatic brain injury
Remote ischemic conditioning (RIC) treatment has been shown to modify levels of traumatic brain injury (TBI) pathology related proteins, however, the mechanism is not widely understood. This study utilized LC-MS/MS to identify protein biomarkers of RIC treatment after TBI in mouse models.
ORGANISM(S): Mus musculus (Mouse) 
2021-06-03 | PXD020420 | Pride
Traumatic brain injury Proteomics Remote ischemic conditioning Biomarkers 
TranscriptomicsThe analysis of differential gene expression after remote ischemic preconditioning of renal ischemia reperfusion injury
To investigate the mechanism by which ischemic preconditioning (IPC) produces tissue tolerance to renal ischemia reperfusion injury in a pig model 15 female Yorkshire pigs were divided into three groups: 1: no IPC and 90 minutes warm ischemia; 2: remote IPC with an early window followed by 90 min wa...
ORGANISM(S): Sus scrofa 
2016-09-02 | E-GEOD-72646 | biostudies-arrayexpress
UnknownPeripheral Mechanisms of Remote Ischemic Conditioning.
Not available
S-EPMC7169943 | biostudies-literature
GenomicsExpression data from plasma exosomal microRNA of rats with remote ischemic conditioning and normal controls
Expression data from plasma exosomal microRNA of rats with remote ischemic conditioning and normal controls
PRJNA816728 | ENA
UnknownChronic remote ischemic conditioning for cardiovascular protection.
Not available
S-EPMC7169952 | biostudies-literature
GenomicsRemote limb ischemic conditioning alleviates nonalcoholic steatohepatitis via extracellular vesicle-mediated muscle-liver crosstalk [hEV_RNAseq]
Remote limb ischemic conditioning alleviates nonalcoholic steatohepatitis via extracellular vesicle-mediated muscle-liver crosstalk [hEV_RNAseq]
PRJNA1075152 | ENA
GenomicsRemote limb ischemic conditioning alleviates nonalcoholic steatohepatitis via extracellular vesicle-mediated muscle-liver crosstalk [EV miRNA]
Remote limb ischemic conditioning alleviates nonalcoholic steatohepatitis via extracellular vesicle-mediated muscle-liver crosstalk [EV miRNA]
PRJNA1075151 | ENA
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