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TranscriptomicsGene expression profiling of advanced murine K-RasG12V lung adenocarcinomas
We aimed to analyze the transcriptional profile of full-blown murine lung adenocarcinomas driven by K-RasG12V oncogene. We used a GEM model of lung adenocarcinoma driven by a resident K-RasG12V oncogene. On average, tumors were collected 10 months after Adeno-CRE infection.
ORGANISM(S): Mus musculus 
2015-12-14 | E-GEOD-65257 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of normal lung cells and K-RasG12V driven hyperplasias
We aimed to analyze the transcriptional profile of lung epithelial cells early after the expression of a resident K-RasG12V oncogene. This approach was based on the rationale that valuable therapeutic targets should be easier to detect in the first stages of tumor development due to tumor heterogene...
ORGANISM(S): Mus musculus 
2015-12-14 | E-GEOD-65256 | biostudies-arrayexpress
UnknownCardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity.
Not available
S-EPMC5992138 | biostudies-literature
UnknownEvaluation of new Corvis ST parameters in normal, Post-LASIK, Post-LASIK keratectasia and keratoconus eyes.
Not available
S-EPMC7105482 | biostudies-literature
ProteomicsDenitrifying phosphorus removal sludge with heavy metals
DPRS treated by Cd2+, Ni2+ and Cr6+. We look into the differences in metaproteome of treated reactors and the control group, and aim to find the resistance mechanisms of DPRS toward heavy metals
ORGANISM(S): Acidobacteriaceae Bacterium A2-4c Escherichia Coli 
2020-06-10 | PXD019707 |
TranscriptomicsInhibitors of the histone lysine demethylase KDM1A are broadly efficacious in AML by evicting the enzyme from chromatin [RNA-Seq]
Investigating the effects of two different classes of KDM1A inhibitors on the transcriptome of AML cell lines 16 different samples with biological replicates. Treatment for 24 and 72 hours with an irreversible KDM1A inhibitor (RN-1) or a reversible KDM1A inhibitor (GSK690) or an inactive isomer of ...
ORGANISM(S): Homo sapiens 
2016-02-10 | E-GEOD-71740 | biostudies-arrayexpress
GenomicsInhibitors of the histone lysine demethylase KDM1A are broadly efficacious in AML by evicting the enzyme from chromatin [ChIP-Seq]
Examine the distribution of KDM1A and the histone H3K4me2 mark on chromatin following treatment with two distinct classes of KDM1A inhibitors - an irreversible inhibitor (RN-1) and a reversible inhibitor (GSK690) 15 samples total from two treated cell lines - 9 from Kasumi-1 and 6 from SKNO-1. Cont...
ORGANISM(S): Homo sapiens 
2016-02-10 | E-GEOD-71739 | biostudies-arrayexpress
UnknownExpanding the chemical space of ionic liquids using conditional variational autoencoders.
Not available
S-EPMC12810713 | biostudies-literature
UnknownWhole genome sequence analysis identifies a PAX2 mutation to establish a correct diagnosis for a syndromic form of hyperuricemia.
Not available
S-EPMC7611017 | biostudies-literature
UnknownAssessment of perioperative cardiac risk using preoperative quantitative flow ratio in patients with coronary artery disease undergoing noncardiac surgery: a retrospective cohort study
Not available
S-EPMC11320557 | biostudies-literature
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