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MetabolomicsExercise Activates Interferon Immune Response of the Liver via Gpld1 to Enhance Antiviral Innate Immunity

Healthy behavioral patterns could modulate organ functions to enhance the body’s immunity. However, whether exercise regulates antiviral innate immunity remains elusive. Here, we found that exercise promotes type-I IFN (IFN-I) production in the liver and enhances IFN-I immune activity of the body...

2024-04-24 | MTBLS7972 | MetaboLights
UnknownMultiply doses of FDC of rosuvastatin and ezetimibe versus rosuvastatin monotherapy in Chinese patients with hypercholesterolemia (ROSE-CH): multicenter, randomized-controlled trial
Not available
S-EPMC12281852 | biostudies-literature
MetabolomicsRoyal jelly and 10-hydroxy-2-decenoic acid mitigate alcoholic fatty liver disease in mice via the gut-microbiota-metabolite axis

Royal jelly (RJ) and its signature bioactive compound, 10-hydroxy-2-decenoic acid (10-HDA), are believed to possess hepatoprotective properties. However, their protective effects and underlying mechanisms against alcoholic fatty liver disease (AFLD) remain unclear. In the present study, we integr...

2026-05-14 | MTBLS14067 | MetaboLights
UnknownComparison of the Oral Calcimimetics Evocalcet and Cinacalcet in East Asian Patients on Hemodialysis with Secondary Hyperparathyroidism.
Not available
S-EPMC10658267 | biostudies-literature
ProteomicsRNF128 aggravates metabolic dysfunction-associated steatotic liver disease progression via stabilization of SCD1
Background: Metabolic dysfunction–associated steatotic liver disease (MASLD) progresses from simple steatosis to metabolic dysfunction–associated steatohepatitis (MASH), yet its therapeutic development has been hampered by pathological complexity and heterogeneity. Methods: Bulk RNA-seq and diet-in...
ORGANISM(S): Mus Musculus 
2026-04-10 | PXD076845 |
ProteomicsEx vivo lung perfusion enhances donor lung preservation in mice via Hippo signaling activation
Ex vivo lung perfusion (EVLP) is a promising technique that allows organ preservation and repair, increasing the number of marginal donor lungs for lung transplantation. This study aimed to establish an EVLP model in mice, and to unveil the molecular mechanisms responsible of EVLP beneficial effects...
ORGANISM(S): Mus Musculus 
2025-07-16 | PXD066193 |
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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