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MetabolomicsDiagnostic Potential of Plasma IgG N-glycans in Discriminating Thyroid Cancer from Benign Thyroid Nodules and Healthy Controls

BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
TranscriptomicsX-inactivation in hESCs
X chromosome inactivation (XCI) is a dosage compensation mechanism in female cells to regulate X-linked gene expression. We report here that subcultures from established lines of female hESCs displayed variations (0-100%) in the expression of XCI markers such as XIST RNA coating and enrichment of h...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-9637 | biostudies-arrayexpress
UnknownZhi Zhu Ma Ren pill relieves constipation in mice through endoplasmic reticulum stress-mediated apoptosis.
Not available
S-EPMC11558397 | biostudies-literature
ProteomicsHistone Lysine β-Hydroxybutyrylation Regulates Drought Response in Rice
Protein post-translational modifications (PTMs), such as acetylation and methylation, are established as crucial epigenetic marks in eukaryotic cells. Recent advances in mass spectrometry have led to the discovery of novel PTMs, including crotonylation, 2-hydroxyisobutyrylation, β-hydroxybutyrylatio...
ORGANISM(S): Oryza sativa (Rice) 
2026-03-09 | PXD059709 | Pride
Rice  histone  lysine β-hydroxybutyrylation  epigenetics 
ProteomicsHistone Lysine β-Hydroxybutyrylation Regulates Drought Response in Rice
Protein post-translational modifications (PTMs), such as acetylation and methylation, are established as crucial epigenetic marks in eukaryotic cells. Recent advances in mass spectrometry have led to the discovery of novel PTMs, including crotonylation, 2-hydroxyisobutyrylation, β-hydroxybutyrylatio...
ORGANISM(S): Oryza sativa (Rice) 
2026-03-09 | PXD059711 | Pride
Rice  histone  lysine β-hydroxybutyrylation  epigenetics 
UnknownLiver X receptor agonist treatment attenuates cardiac dysfunction in type 2 diabetic db/db mice.
Not available
S-EPMC4245833 | biostudies-literature
TranscriptomicsDeep Sequencing identifies regulated small RNAs in Dugesia japonica
We applied Illumina sequencing to identify microRNAs (miRNAs) and piwi-interacting small RNAs (piRNAs) in Dugesia japonica. Dugesia were cut up after seven day’s starvation. DJ1 is the whole Dugesia body, DJ2 is the head part, DJ3 is the tail part, DJ4 is the left part and DJ5 is the right part. Tot...
ORGANISM(S): Dugesia japonica 
2013-01-22 | E-GEOD-43188 | biostudies-arrayexpress
GenomicsHeterochromatin remodeling by CDK12 contributes to learning in Drosophila
We describe the epigenetic profiling of the H3K9me2 and HP1a in Drosophila third instar larvae before and after CDK12 depletion by RNA interference (RNAi). Here we show that CDK12 regulates heterochromatin dynamics in Drosophila chromosomes. Depletion of CDK12 induces the increased HP1a and H3K9me2 ...
ORGANISM(S): Drosophila melanogaster 
2015-11-02 | E-GEOD-63011 | biostudies-arrayexpress
UnknownIdentification and Characterization of a Novel Di-(2-ethylhexyl) Phthalate Hydrolase from a Marine Bacterial Strain <i>Mycolicibacterium phocaicum</i> RL-HY01.
Not available
S-EPMC12428281 | biostudies-literature
UnknownEvidence of Echolocation in the Common Shrew from Molecular Convergence with Other Echolocating Mammals.
Not available
S-EPMC7262541 | biostudies-literature
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