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TranscriptomicsExpression data from HeLa cells after MBD2 and MBD3 knock down
The heterogeneous collection of NuRD complexes can be grouped into the MBD2 or MBD3 containing complexes MBD2-NuRD and MBD3-NuRD. MBD2 is known to bind to methylated CpG sequences in vitro in contrast to MBD3. Although functional differences have been described, a direct comparison of MBD2 and MBD3 ...
ORGANISM(S): Homo sapiens 
2013-02-08 | E-GEOD-41003 | biostudies-arrayexpress
GenomicsCTCF/CP190 and ISWI dependent regulation of nucleosome occupancy [MNase-seq]
MNase-seq was performed in order to analyze changes in nucleosomal occupancy after depletion of CTCF/P190 and ISWI from Drosophila S2 cells MNase-seq from Drosophila S2 nuclei after CTCF/CP190 or ISWI-specific RNAi treatment
ORGANISM(S): Drosophila melanogaster 
2014-08-11 | E-GEOD-51599 | biostudies-arrayexpress
GenomicsCTCF/CP190 and ISWI dependent regulation of nucleosome occupancy [ChIP-seq]
H3-ChIP-seq was performed in order to analyze changes in nucleosomal occupancy after depletion of CTCF/P190 and ISWI from Drosophila S2 cells Histone H3 ChIP-seq from Drosophila S2 cells after CTCF/CP190 or ISWI-specific RNAi treatment
ORGANISM(S): Drosophila melanogaster 
2014-08-11 | E-GEOD-51598 | biostudies-arrayexpress
GenomicsGenome-wide identification of MBD2 and MBD3 binding sites by ChIP-seq
The heterogeneous collection of NuRD complexes can be grouped into the MBD2 or MBD3 containing complexes MBD2-NuRD and MBD3-NuRD. Although functional differences have been described, a direct comparison of MBD2 and MBD3 in respect to genome-wide binding and function has been lacking. Here we show a ...
ORGANISM(S): Homo sapiens 
2013-02-08 | E-GEOD-41006 | biostudies-arrayexpress
TranscriptomicsAnalysis of genome-wide binding of the insulator factors CTCF and CP190
We identified about 3000 CTCF sites in the genome. In addition to binding to CTCF sites we found CP190 to bind to transcriptional start sites of actively transcribed genes where it inversely correlates with nucleosome occupancy. Keywords: ChIP-chip CTCF and CP190 ChIP. 2 biological replicates per e...
ORGANISM(S): Drosophila melanogaster 
2010-05-05 | E-GEOD-12749 | biostudies-arrayexpress
GenomicsCTCF/CP190 and ISWI dependent regulation of nucleosome occupancy
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2014-08-11 | E-GEOD-51600 | biostudies-arrayexpress
GenomicsNucleosome dynamics specifies genome-wide binding of the male germ cell gene regulator CTCFL and of CTCF [ChIP-Seq]
CTCF and CTCFL DNA binding profile in CTCFL induced and non-induced ES cells.CTCF is a highly conserved and essential zinc finger protein that in conjunction with cohesin organizes chromatin into loops, thereby regulating gene expression and epigenetic events. The function of CTCFL or BORIS, the tes...
ORGANISM(S): Mus musculus 
2012-07-25 | E-GEOD-34094 | biostudies-arrayexpress
TranscriptomicsNucleosome dynamics specifies genome-wide binding of the male germ cell gene regulator CTCFL and of CTCF [MoGene-1_0 Expression]
CTCFL binding to DNA and the effect of CTCFL expression in ES cells RNA extracted from CTCFL induced and non-induced ES cells was hybridized on Affymetrix Mouse Gene 1.0ST arrays
ORGANISM(S): Mus musculus 
2012-07-24 | E-GEOD-34092 | biostudies-arrayexpress
TranscriptomicsNucleosome dynamics specifies genome-wide binding of the male germ cell gene regulator CTCFL and of CTCF [Mouse430_2 Expression]
The effect of CTCFL mutation on the transcriptional program in testes Testis RNA extracted from CTCFL wildtype and mutant mice was hybridized on Affymetrix Mouse430_2 arrays
ORGANISM(S): Mus musculus 
2012-07-24 | E-GEOD-34091 | biostudies-arrayexpress
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