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TranscriptomicsThe metalloregulatory site in Streptococcus pneumoniae AdcR, a zinc-activated MarR-family repressor
Streptococcus pneumoniae D39 AdcR (adhesion competence repressor) is the first metal-sensing member of the MarR (multiple antibiotic resistance repressor) family to be characterized. Expression profiling of a ∆adcR strain grown in liquid culture under microaerobic conditions revealed that transcr...
ORGANISM(S): Streptococcus pneumoniae 
2010-10-01 | E-GEOD-21506 | biostudies-arrayexpress
TranscriptomicsMammalian TRIM71 as repressor of mRNAs that inhibits translation and affects mRNA stability
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-01-22 | E-GEOD-37714 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse embryonic stem cells upon TRIM71 KD and parental ctrl cells
We identify mammalian TRIM71 as repressor of mRNAs that inhibits translation and affects mRNA stability. In this data set we compare the expression profile of mouse ES upon Trim71 KD versus that of the parental cells. Experiment was performed in triplicate.
ORGANISM(S): Mus musculus 
2013-01-22 | E-GEOD-37712 | biostudies-arrayexpress
TranscriptomicsRegulation of PTSBio by transcriptional repressor NigR
In this study we analyzed the transcriptional regulation of the operon (OBio) encoding the PTSBio and showed that it was repressed by NigR, a LacI-like transcriptional regulator. To elucidate the role of NigR in regulation of S. mutans carbohydrate transporters we performed full genome expression mi...
ORGANISM(S): Streptococcus mutans UA159 
2015-06-22 | E-GEOD-63213 | biostudies-arrayexpress
TranscriptomicsExpression data from HEK293 Flp-In cells constitutivly expressing FLAG-HA-tagged TRIM71 and that of the parental cell line
We identify mammalian TRIM71 as repressor of mRNAs that inhibits translation and affects mRNA stability. In this data set we compare the expression profile of human HEK293 Flp-In cells stably expressing TRIM71 to that of the parental cells, not expressing TRIM71 protein. Experiment was performed in ...
ORGANISM(S): Homo sapiens 
2013-01-22 | E-GEOD-37713 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HEK 293 cells with or without overexpression of the repressor ICER treated by forskolin at 0,1,2,4 and 8 hours
HEK 293 cells with or without overexpression of ICER IIg were treated with forskolin for 0, 1 h, 2 h, 4 h or 8 h. The cell line used in the experiments is HEK 293 cells stable transfected with tetracycline-inducible ICER (Inducible cAMP early repressor) expression.
ORGANISM(S): Homo sapiens 
2010-01-01 | E-MTAB-122 | biostudies-arrayexpress
ModelsKarapetyan2016 - Genetic oscillatory network - Repressor Titration Circuit (RTC)
Karapetyan2016 - Genetic oscillatory network - Repressor Titration Circuit (RTC) This model is described in the article: Role of DNA binding sites and slow unbinding kinetics in titration-based oscillators. Karapetyan S, Buchler NE. Phys Rev E Stat Nonlin Soft Matter Phys ...
2024-09-02 | BIOMD0000000587 | BioModels
TranscriptomicsProfiling the target genes for ZIP repressor in MCF-7
Using ChIP-DSL technology from Aviva Systems Biology to find out the whole genome targets for ZIP transcription repressor We analyzed arrays using specific ZIP antibody and negative control to acquire the enriched ratio of each gene
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-13905 | biostudies-arrayexpress
TranscriptomicsComplex regulation of the PEP carboxykinase gene pck and characterization of its GntR-type regulator IolR as a repressor of myo-inositol utilization genes in Corynebacterium glutamicum
DNA affinity chromatography with the promoter region of the Corynebacterium glutamicum pck gene, encoding phosphoenolpyruvate carboxykinase (PEPCk), led to the isolation of four transcriptional regulators, i.e., RamA, GntR1, GntR2 and IolR. Determination of the PEPCk activity of the deletion mutant...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2013-07-29 | E-GEOD-44812 | biostudies-arrayexpress
ProteomicsThe CDK Pho85 inhibits Whi7 Start repressor to promote cell cycle entry in budding yeast
Pho85 is a multifunctional CDK that signals to the cell when environmental conditions are favorable. It has been connected to cell cycle control, mainly in Start where it promotes the G1/S transition. Here we describe that the Start repressor Whi7 is a key target of Pho85 in the regulation of cell c...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2023-12-13 | PXD046448 | Pride
Dda-pasef Phospho proteomics 
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