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TranscriptomicsRegulation of PTSBio by transcriptional repressor NigR
In this study we analyzed the transcriptional regulation of the operon (OBio) encoding the PTSBio and showed that it was repressed by NigR, a LacI-like transcriptional regulator. To elucidate the role of NigR in regulation of S. mutans carbohydrate transporters we performed full genome expression mi...
ORGANISM(S): Streptococcus mutans UA159 
2015-06-22 | E-GEOD-63213 | biostudies-arrayexpress
ProteomicsA method for targeting a specified segment of DNA to a bacterial microorganelle
Our work presents a protocol for the encapsulation and subsequent affinity isolation of the proteinaceous compartment carrying a DNA segment. To this end, we have repurposed the microcompartment of Citrobacter freundii for propaneadiol utilisation (Pdu) and constructed a LacI transcription repressor...
ORGANISM(S): Escherichia coli 
2022-08-11 | PXD035877 | Pride
Escherichia coli Propanediol utilisation (pdu) microcompartment Repressor laci Citrobacter freundii 
UnknownStructure-guided approach to site-specific fluorophore labeling of the lac repressor LacI.
Not available
S-EPMC5983854 | biostudies-literature
TranscriptomicsEffect of LacI (lac repressor) on transcription in Salmonella
Salmonella is an important enteric pathogen that causes a spectrum of diseases varying from mild gastroenteritis to life threatening typhoid fever. Salmonella does not have lac operon. However, E. Coli, Salmonella’s close relative, has lac operon. Being an enteric pathogen like E. coli, Salmonella w...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 
2009-05-07 | GSE15950 | GEO
TranscriptomicsUnderstanding the Regulatory Networks of Three LacI Transcriptional Repressors in Clostridium thermocellum DSM1313
Clostridium thermocellum is a candidate for cellulosic ethanol production. It expresses enzymes for both cellulose solubilization and its fermentation to produce lignocellulosic ethanol. Understanding how this organism regulates gene expression is of importance for developing a better fundamental u...
ORGANISM(S): Ruminiclostridium thermocellum DSM 1313 
2015-10-31 | E-GEOD-68423 | biostudies-arrayexpress
UnknownRegulation of D-xylose metabolism in Caulobacter crescentus by a LacI-type repressor.
Not available
S-EPMC2168598 | biostudies-literature
GenomicsDeep Representation Learning Improves Prediction of LacI-mediated Transcriptional Repression
Deep Representation Learning Improves Prediction of LacI-mediated Transcriptional Repression
PRJNA732423 | ENA
UnknownOptoLacI: optogenetically engineered lactose operon repressor LacI responsive to light instead of IPTG.
Not available
S-EPMC11260447 | biostudies-literature
TranscriptomicsUnderstanding the Regulatory Networks of Three LacI Transcriptional Repressors in Clostridium thermocellum DSM1313
Clostridium thermocellum is a candidate for cellulosic ethanol production. It expresses enzymes for both cellulose solubilization and its fermentation to produce lignocellulosic ethanol. Understanding how this organism regulates gene expression is of importance for developing a better fundamental un...
ORGANISM(S): Acetivibrio thermocellus DSM 1313 
2015-10-31 | GSE68423 | GEO
TranscriptomicsEffect of LacI (lac repressor) on transcription in Salmonella
Salmonella is an important enteric pathogen that causes a spectrum of diseases varying from mild gastroenteritis to life threatening typhoid fever. Salmonella does not have lac operon. However, E. Coli, Salmonella’s close relative, has lac operon. Being an enteric pathogen like E. coli, Salmonella...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 
2010-05-19 | E-GEOD-15950 | biostudies-arrayexpress
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