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Ter-polymer (MMA/EGDMA/1,2-Epoxy-5-Hexene) is fabricated via the polymerization using ethylene glycol di-methacrylate (EGDMA) as polar crosslinker. The oxirane groups of ter-polymer are immobilized with cysteic acid to enhance the hydrophilicity of HILIC sorbent. The enrichment efficacy is evaluated...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD030890 | Pride
This study evaluates changes in metabolite levels in hepatocellular carcinoma (HCC) cases vs. patients with liver cirrhosis by analysis of human blood plasma using gas chromatography coupled with mass spectrometry (GC-MS). Untargeted metabolomic analysis of plasma samples from participants recruited...
2015-08-13 | MTBLS105 | MetaboLights
Although hepatocellular carcinoma (HCC) has been subjected to continuous investigation and its symptoms are well-known, early stage diagnosis of this disease remains difficult and the survival rate after diagnosis is typically very low (3−5%). Early and accurate detection of metabolic changes in the...
2013-06-30 | MTBLS19 | MetaboLights
Characterizing the metabolic changes pertaining to hepatocellular carcinoma (HCC) in patients with liver cirrhosis is believed to contribute towards early detection, treatment, and understanding of the molecular mechanisms of HCC. In this study, we compare metabolite levels in sera of 78 HCC cases w...
Copy number analysis of human GBM samples were performed, and a high frequency of deletions of the PTPRD gene on chromosome 9p23-24.1 were identified. Keywords: SNP microarray, glioblastoma multiforme, copy number, amplification, deletion Genomic DNA from 58 GBM tumor samples were hybridized to Aff...
ORGANISM(S): Homo sapiens 
Gamma tocotrienol induces apoptosis in breast cancer cells however, the molecular mechanisms are not completely understood. We used microarrays to detail the global programme of gene expression underlying the effects of gamma tocotrienols on MCF-7 cells and identified distinct classes of up-regulate...
ORGANISM(S): Homo sapiens 
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