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T Cell stretch-enhancers are vulnerable to Jak inhibitor tofacitinib Treatment of T cells with the Janus kinase (JAK) inhibitor, tofacitinib, disproportionately altered the expression of RA risk genes with stretech-enhancer (SE) structures.
ORGANISM(S): Homo sapiens 
Repeat experiments of CD8+ pmel effector cells following one and two rounds of restimulation
ORGANISM(S): Mus musculus 
Central memory tumor-reactive CD8+ T cells confer superior antitumor immunity compared to effector memory T cells
ORGANISM(S): Mus musculus 
Through their functional diversification, CD4+ T cells play key roles in both driving and constraining immune-mediated pathology. Transcription factors are critical in the generation and maintenance of cellular diversity and negative regulators antagonistic to alternate fates often act in conjunctio...
ORGANISM(S): Mus musculus 
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