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Resveratrol (3,5,4'-trihydroxystilbene) extends the lifespan of diverse species including yeast, worms, and flies. In these organisms, lifespan extension is dependent on Sir2, a conserved deacetylase proposed to underlie the beneficial effects of caloric restriction (CR). Here we show that resveratr...
ORGANISM(S): Mus musculus 
The obese, insulin resistant state is characterized by impairments in lipid metabolism. Dietary polyphenols might improve these deteriorations. We have previously shown that 3-days supplementation of combined Epigallocatechin-gallate and Resveratrol (E+R) increased energy expenditure, which was acco...
ORGANISM(S): Homo sapiens 
Two long serial analysis of gene expression (LongSAGE) libraries of germinating conidia of Botrytis cinerea were generated with and without resveratrol treatments for unraveling the antifungal mechanisms of this phytoalexin by global transcriptome analysis – 82,786 total tags and a minimum of 15,665...
ORGANISM(S): Botrytis cinerea 
2010-04-06 | GSE11090 | GEO
Background: Transcription control of mitochondrial metabolism is essential for cellular function. A better understanding of this process will aid the elucidation of mitochondrial disorders, in particular of the many genetically unsolved cases of oxidative phosphorylation (OXPHOS) deficiency. Yet, to...
ORGANISM(S): Homo sapiens 
In this study, grapevine cells control and elicited with 50 mM methylated cyclodextrins and 0.1 mM methyl jasmonate, that are known to accumulate extracellular resveratrol, were used to obtain membrane enriched fractions, specifically tonoplast and plasma membrane enriched fractions with the aim of ...
ORGANISM(S): Vitis vinifera (Grape) 
2025-05-06 | PXD048454 | Pride
The gas-1(fc21) mutation affects the 49 kD subunit of complex I, decreasing the rate of complex I-dependent oxidative phosphorylation. This is a model for human mitochondrial respiratory chain disease. NAD+ and PPAR-modifying drugs may confer benefits with respect to lifespan in these short-lived mu...
ORGANISM(S): Caenorhabditis elegans 
Characterizing the transcriptomic profile of the cortex within the long-term window of ischemic tolerance mediated by resveratrol preconditioning
To identify novel genes and adaptations induced by resveratrol preconditioning that could promote long-term cerebral ischemic tolerance. After analyzing the results, we identified only 155 differentially expressed genes among which the majority of genes consisting of 126 were downregulated and only ...
ORGANISM(S): Mus musculus 
2019-01-01 | GSE113298 | GEO
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