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ProteomicsBasement Membranes from Human Retinal Blood Vessels, Inner Limiting Membranes, and Lens Capsules
Three types of BMs from adult human eyes, the inner limiting membrane, the retinal vascular BMs and the lens capsule, were isolated for analysis by 1D-SDS-PAGE and LC-MS/MS.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081772 | MassIVE
TranscriptomicsTranscription profiling of human donor-matched retinal and choroidal vascular endothelial cells
Consistent with clinical observations that posterior uveitis frequently involves the retinal vasculature and recent recognition of vascular heterogeneity, we hypothesized that retinal vascular endothelium was a cell population of unique molecular phenotype. Donor-matched cultures of primary retinal ...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7850 | biostudies-arrayexpress
ProteomicsComparative proteomic study of healthy retinal vascular tree from human donor eyes and fibrovascular membrane of PDR patients
In the retinal vascular unit, direct communication between pericytes (PCs) and endothelial cells (ECs) is important for vessel stability and maintenance of the properties of the blood-retinal barrier (BRB). ECs and PCs sharing a common basement membrane throughout vasculogenesis tend to lose vessel ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD052211 | Pride
Human 
TranscriptomicsRetinal vessel microarray
We sought to identify differentially expressed genes in several animal models of a retinal disease exhibiting vascular abnormalities and/or angiogenesis compared to control animals. Retinal microvessels were isolated from three models (RD1, Grhl3ct (Curlytail), VLDLR knock-out) and one rat model (R...
ORGANISM(S): Rattus norvegicus 
2013-09-13 | E-MEXP-3323 | biostudies-arrayexpress
TranscriptomicsThe transcriptional response to Norrin/Fz4 signaling
Using mice with targeted gene mutations, we identify (1) distinct roles for different canonical Wnt signaling components in central nervous system (CNS) vascular development and in the specification of the blood-brain and blood-retina barriers (BBB and BRB) and (2) differential sensitivities of the ...
ORGANISM(S): Mus musculus 
2014-06-05 | E-GEOD-56461 | biostudies-arrayexpress
OtherA proteomic view of basement membranes from human retinal blood vessels, inner limiting membranes, and lens capsules.
Data from ProteomeXchange, PXD ID: PXD001025. Experiment: ILM, file: ILM-2.mzml. Published as part of J Proteome Res. 2014 Jul 2 . From the Abstract: {{i}} Basement membranes (BMs) are extracellular matrix sheets comprising the laminins, type IV collagens, nidogens, and the heparan sulfate proteogl...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310002171 | GPMDB
Resource Reanalysis 
ProteomicsAn integrative multi-omics analysis reveals microRNA-143 as potential therapeutics to attenuate retinal angiogenesis
Retinal neovascularization is a severe complication of several neovascular retinal diseases, including proliferative diabetic retinopathy, central retinal vein occlusion and retinopathy of prematurity. MicroRNAs (miRNAs) are master regulators of gene expression that play an important role in retinal...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD029706 | Pride
Microrna Endothelial cells Oxygen-induced retinopathy Retinal neovascularization Next-generation sequencing 
UnknownCharacterization of the Canine Retinal Vasculature With Optical Coherence Tomography Angiography: Comparisons With Histology and Fluorescein Angiography.
Not available
S-EPMC8710516 | biostudies-literature
UnknownGenetic determinants of hyaloid and retinal vasculature in zebrafish.
Not available
S-EPMC2169232 | biostudies-literature
TranscriptomicsRetinal gene expression of low-density lipoprotein receptor-related protein 5 (Lrp5) knockout mice
Retinal gene expression was assessed from postnatal day (P) 8 old low-density lipoprotein receptor-related protein 5 (Lrp5) knockout mice with a Illumina mouse-WG6 expression BeadChip. RNA was extracted from the retinas of P8 Lrp5 knockout and wild type mice (n=3 each group). Total RNA (1ug each) we...
ORGANISM(S): Mus musculus 
2012-05-21 | E-GEOD-32145 | biostudies-arrayexpress
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