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TranscriptomicsRetrograde signalling during caused by heritable mitochondrial dysfunction is partly mediated by ANAC017 and improves plant performance.
Mitochondria are crucial for plant viability and are able to communicate information on their functional status to the cellular nucleus via retrograde signalling, thereby affecting gene expression. It is currently unclear if retrograde signalling in response to constitutive mitochondrial biogenesis ...
ORGANISM(S): Arabidopsis thaliana 
2016-07-28 | E-MTAB-4655 | biostudies-arrayexpress
TranscriptomicsSignaling to Transcription Networks in the Neuronal Retrograde Injury Response
Retrograde signaling from axon to soma activates intrinsic regeneration mechanisms in lesioned peripheral sensory neurons; however, the links between axonal injury signaling and the cell body response are not well understood. Here, we used phosphoproteomics and microarrays to implicate ~900 phosphop...
ORGANISM(S): Rattus norvegicus 
2010-12-29 | E-GEOD-26350 | biostudies-arrayexpress
TranscriptomicsRetrograde bilin signaling enables Chlamydomonas greening and phototrophic survival
Here we show that the phytochrome-less chlorophyte Chlamydomonas reinhardtii retains a functional pathway to synthesize the linear tetrapyrrole (bilin) precursor of the phytochrome chromophore. Reverse genetic, metabolic inactivation and bilin rescue experiments establish that this pathway is needed...
ORGANISM(S): Chlamydomonas reinhardtii 
2013-01-10 | E-GEOD-40031 | biostudies-arrayexpress
TranscriptomicsSigma2 and Sigma6-mediated plastid retrograde signals control nuclear gene expression in Arabidopsis
Retrograde signaling from the chloroplast to the nucleus is necessary to regulate the chloroplast proteome during development and fluctuating environmental conditions. Although the specific chloroplast process(es) that must occur and the nature of the signal(s) that exits the chloroplast are not wel...
ORGANISM(S): Arabidopsis thaliana 
2012-09-18 | E-MTAB-4338 | biostudies-arrayexpress
TranscriptomicsCyclin-dependent protein kinase E;1 (CDKE;1) is an essential component for mitochondrial retrograde signalling in Arabidopsis thaliana
Stresses that target mitochondrial function lead to altered transcriptional responses for 100-1000s of genes genome wide, and are signalled via retrograde signalling pathways within the cell. rao1 mutants contain a mutation in a gene encoding a Cyclin-Dependant Kinase E;1 and cannot induce stress re...
ORGANISM(S): Arabidopsis thaliana 
2013-01-28 | E-GEOD-36011 | biostudies-arrayexpress
TranscriptomicsIdentification of target genes of translation-dependent signalling in Arabidopsis
Changes ins organellar gene expression trigger retrograde signalling. Prolyl-tRNA synthetase (PRORS1) is located in chloroplasts and mitochondria. Thus, prors1-2 mutants are impaired in chloroplast and mitochondrial gene expression. The effects of the prors1-2 mutation on the global transcriptome we...
ORGANISM(S): Arabidopsis thaliana 
2014-01-31 | E-GEOD-54573 | biostudies-arrayexpress
GenomicsRetrograde signalling during caused by heritable mitochondrial dysfunction is partly mediated by ANAC017 and improves plant performance.
Retrograde signalling during caused by heritable mitochondrial dysfunction is partly mediated by ANAC017 and improves plant performance.
PRJEB14313 | ENA
ProteomicsRetrograde signalling mediates cellular adaptation to mitochondrial DNA copy number alterations
Eukaryotic cells maintain multiple copies of the mitochondrial genome, which is essential for cellular metabolism. Accordingly, alterations in the mitochondrial DNA (mtDNA) copy number are associated with severe human diseases and ageing. However, the mechanisms through which cells regulate mtDNA co...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-07-26 | PXD081636 | Pride
Mitochondria Yeast Retrograde signalling Cell size 
UnknownMitochondrial retrograde signalling in neurological disease.
Not available
S-EPMC7209953 | biostudies-literature
TranscriptomicsCommunication between mitochondria and nucleus: defining a retrograde response in fission yeast
Retrograde response was widely studied in budding yeast but the main transcription factors that transmit it (RTG1,2 and 3) are not conserved in other organisms, thus it is interesting to study how communication between mitochondria and nucleus evolved in distantly related fission yeast, and which ar...
ORGANISM(S): Schizosaccharomyces pombe 
2016-11-01 | E-MTAB-4520 | biostudies-arrayexpress
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