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TranscriptomicsThe regenerative response in the pig liver remnant varies with the degree of resection and rise in portal pressure.
Following parenchymal loss, the liver regenerates restoring normal mass and metabolic function. Prevailing theories on triggering events leading to regeneration include humoral, metabolic and flow-mediated mechanisms, the latter emphasizing the importance of shear stress mediated nitric oxide (NO) r...
ORGANISM(S): Sus scrofa 
2008-01-14 | E-GEOD-6860 | biostudies-arrayexpress
TranscriptomicsIs Increased Sinusoidal Flow in the Liver Remnant the primary Stimulus to Regeneration after partial Hepatectomy
The impact of portal arterialization on the liver parenchyma was studied in a series of six pigs with aortoportal shunting of liver segments II, III and IV (and 6 sham animals). Gene expression in the arterialized segments was compared to expression in sham animals. Primary endpoints were gene expre...
ORGANISM(S): Sus scrofa 
2010-05-07 | E-GEOD-13683 | biostudies-arrayexpress
TranscriptomicsThe Genetic Regulation of the Terminating Phase of Liver Regeneration
The liver regeneration process terminates when the normal liver-mass/body-weight ratio of 2.5 % has been re-established. We aimed to generate and analyse global expression profiles to study the genetic interactions in relation to liver regeneration, to illuminate the genetic interactions between gen...
ORGANISM(S): Sus scrofa 
2013-01-01 | E-GEOD-14396 | biostudies-arrayexpress
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