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GenomicsGenome-Wide And Phase-Specific DNA-Binding Rhythms Of BMAL1 Control Circadian Output Functions In Mouse Liver
Using chromatin immuno-precipitation (ChIP) combined with deep sequencing (ChIP-seq) we obtained a time resolved and genome-wide map of BMAL1 binding in mouse liver, which allowed to identify over two thousand binding sites with peak binding narrowly centered around Zeitgeber time (ZT) 6. Annotation...
ORGANISM(S): Mus musculus 
2011-02-23 | E-GEOD-26602 | biostudies-arrayexpress
TranscriptomicsCIRP, a cold-inducible RNA-binding protein, modulates circadian gene expression posttranscriptionally
In mammalian tissues circadian gene expression can be driven by local oscillators or systemic signals controlled by the master pacemaker in the suprachiasmatic nucleus. Here we show that simulated body temperature cycles, but not peripheral oscillators, can control the rhythmic expression of Cold-In...
ORGANISM(S): Mus musculus 
2012-08-24 | E-GEOD-37685 | biostudies-arrayexpress
ProteomicsNeddylation is a global orchestrator of the molecular network driving Schwann cell myelination
Axonal myelination is essential for neuronal function and health. In peripheral nerves, deficient myelination is responsible for the morbidity of various forms of inherited or acquired neuropathies, including Charcot-Marie-Tooth disease and diabetic neuropathy. Decades of research have uncovered a c...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-06-16 | PXD043917 | Pride
Ptms Neddylation Ubiquitin-like Schwann cells Label free 
ProteomicsTRAJECTORY ANALYSIS OF HEPATIC STELLATE CELL DIFFERENTIATION REVEALS METABOLIC REGULATION OF CELL COMMITMENT AND FIBROSIS
Defining the trajectory of cells during differentiation and disease is key for uncovering the mechanisms driving cell fate and identity. However, trajectories of human cells remain largely unexplored due to the challenges of studying them with human samples. In this study, we investigated the proteo...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058290 | Pride
Ipscs Dihscs Rora Metabolic plasticity 
TranscriptomicsLongitudinal scRNAseq profiling of memory B cells in severe COVID19 patients
Memory B cells play a fundamental role in host defences against viruses. This dataset aimed at understanding their maturation and stability in the context of SARS-CoV-2 infection and consist of a longitudinal single-cell and repertoire profiling of the B cell response up to six months in four severe...
ORGANISM(S): Homo sapiens 
2021-01-31 | E-MTAB-9995 | biostudies-arrayexpress
UnknownConsiderations and consequences of allowing DNA sequence data as types of fungal taxa.
Not available
S-EPMC6048565 | biostudies-literature
UnknownFungal Planet description sheets: 868-950.
Not available
S-EPMC6712538 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownRisk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
Not available
S-EPMC6306365 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
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