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ProteomicsProduction and properties of adhesin-free gingipain proteinase RgpA
To obtain RgpA free of adhesin requires a means of separating the RgpA catalytic domain from the adhesins domains or adaptation of a method to prevent RgpA complex association.In this study, recombinant suicide plasmids were designed for use in homologous recombination with the rgpA locus so as to p...
ORGANISM(S): Porphyromonas gingivalis W50 
2023-06-02 | PXD036859 | Pride
Lc-msms 
UnknownSignificance of Reynolds Number Consistency in Non-Newtonian Hemodynamic Simulations: Insights from Fontan Circulation.
Not available
S-EPMC12777659 | biostudies-literature
UnknownThe exchanged EF-hands in calmodulin and troponin C chimeras impair the Ca²⁺-induced hydrophobicity and alter the interaction with Orai1: a spectroscopic, thermodynamic and kinetic study.
Not available
S-EPMC4349623 | biostudies-literature
TranscriptomicsAnalysis of the transcriptional response of Candida parapsilosis following exposure to farnesol
We used the results of a genome sequence survey to design and manufacture partial genomic microarrays that were applied to determining the transcriptional response of C. parapsilosis to the presence of exogenous farnesol. Keywords: drug response, farnesol, Transcriptional profiling was performed fo...
ORGANISM(S): Candida parapsilosis 
2010-06-11 | E-GEOD-6318 | biostudies-arrayexpress
MetabolomicsA pathogen-specific isotope tracing approach reveals metabolic activities and fluxes of intracellular Salmonella

Pathogenic bacteria proliferating inside mammalian host cells need to rapidly adapt to the intracellular environment. How they achieve this and scavenge essential nutrients from the host has been an open question due to the difficulties in distinguishing between bacterial and host metabolites

2023-08-02 | MTBLS1275 | MetaboLights
TranscriptomicsThe Snf1-Related Kinase, Hunk, Is Essential for Mammary Tumor Metastasis
We previously identified a novel SNF1/AMPK-related protein kinase, Hunk, from a mammary tumor arising in an MMTV-neu transgenic mouse. The function of this kinase is unknown. Using targeted deletion in mice, we now demonstrate that Hunk is required for the metastasis of c-myc-induced mammary tumors,...
ORGANISM(S): Mus musculus 
2009-12-31 | E-GEOD-14226 | biostudies-arrayexpress
UnknownTime-Resolved Imaging Reveals Heterogeneous Landscapes of Nanomolar Ca(2+) in Neurons and Astroglia.
Not available
S-EPMC4622934 | biostudies-literature
UnknownA study of dopant incorporation in Te-doped GaAsSb nanowires using a combination of XPS/UPS, and C-AFM/SKPM.
Not available
S-EPMC8050051 | biostudies-literature
UnknownPointBreak: a randomized phase III study of pemetrexed plus carboplatin and bevacizumab followed by maintenance pemetrexed and bevacizumab versus paclitaxel plus carboplatin and bevacizumab followed by maintenance bevacizumab in patients with stage IIIB or IV nonsquamous non-small-cell lung cancer.
Not available
S-EPMC4881367 | biostudies-literature
UnknownThe RgpB C-terminal domain has a role in attachment of RgpB to the outer membrane and belongs to a novel C-terminal-domain family found in Porphyromonas gingivalis.
Not available
S-EPMC1595369 | biostudies-literature
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