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ProteomicsSpecific sDMA Modifications on the RGG/RG Motif of METTL14 Regulate Its Function in AML
Protein arginine methylations are crucial post-translational modifications (PTMs) in eukaryotes, playing a significant regulatory role in diverse biological processes. Different forms of arginine methylations are known to co-exist within densely modified arginine-rich protein regions. However, pinpo...
ORGANISM(S): Homo Sapiens 
2024-08-05 | PXD054570 |
GenomicsComparison of the specificities of the RGG/RG-domains of FMR1, FXR1 and FXR2 for small RNA
In previous studies, we identified a sequence motif (GDCGG) in almost all microRNAs downregulated in the serum of patients with amyotrophic lateral sclerosis. We found that FMR1, FXR1 and FXR2 directly and specifically interact with microRNAs containing the GDCGG motif via their RGG/RG-domains. Here...
ORGANISM(S): Homo sapiens synthetic construct 
2021-04-21 | GSE101067 | GEO
UnknownThe RGG/RG motif of AUF1 isoform p45 is a key modulator of the protein's RNA chaperone and RNA annealing activities.
Not available
S-EPMC6550787 | biostudies-literature
UnknownThe RNA-Binding Domain of hnRNP U Extends beyond the RGG/RG Motifs.
Not available
S-EPMC11449452 | biostudies-literature
UnknownSpecific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML.
Not available
S-EPMC11889898 | biostudies-literature
ProteomicsPRMT6 substrate specificity analysis
Protein arginine methyltransferase 6 (PRMT6) catalyses the asymmetric dimethylation of arginines on numerous substrate proteins within the human cell. In particular, PRMT6 methylates histone H3 arginine 2 (H3R2) which affects both gene repression and activation. However, the substrate specificity of...
ORGANISM(S): Homo Sapiens 
2021-03-31 | PXD016711 | panorama
UnknownThe RNA-binding Selectivity of the RGG/RG Motifs of hnRNP U is Abolished by Elements Within the C-terminal Intrinsically Disordered Region.
Not available
S-EPMC11441334 | biostudies-literature
GenomicsHomo sapiens
Comparison of the specificities of the RGG/RG-domains of FMR1, FXR1 and FXR2 for small RNA
PRJNA393667 | ENA
UnknownORF73 LANA homologs of RRV and MneRV2 contain an extended RGG/RG-rich nuclear and nucleolar localization signal that interacts directly with importin β1 for non-classical nuclear import.
Not available
S-EPMC5929975 | biostudies-literature
UnknownArginine methylation of the DDX5 helicase RGG/RG motif by PRMT5 regulates resolution of RNA/DNA hybrids
Not available
S-SCDT-EMBOJ-2018-100986 | biostudies-other
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