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ProteomicsThe proteomic and transcriptomic landscapes altered by Rgg2/3 activity in Streptococcus pyogenes
Streptococcus pyogenes, otherwise known as Group A Streptococcus (GAS), is an important and highly adaptable human pathogen with the ability to cause both superficial and severe diseases. Understanding how S. pyogenes senses and responds to its environment will likely aid in determining how it cause...
ORGANISM(S): Streptococcus pyogenes NZ131 
2022-10-04 | PXD033703 | Pride
Rgg3 Streptococcus pyogenes Rgg2 Quorum sensing 
TranscriptomicsIdentifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model
Streptococcus pyogenes is an obligate human pathobiont associated with many disease states. Here, we present a novel model of S. pyogenes infection using intact murine epithelium. From this model, we were able to perform RNA sequencing to evaluate the genetic changes undertaken by both the bacterium...
ORGANISM(S): Mus musculus Streptococcus pyogenes NZ131 
2023-07-17 | GSE237018 | GEO
UnknownStructure-function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay.
Not available
S-EPMC7533842 | biostudies-literature
UnknownIdentification of Heterotrimeric G Protein γ3 Subunit in Rice Plasma Membrane.
Not available
S-EPMC6274724 | biostudies-literature
UnknownAntagonistic Rgg regulators mediate quorum sensing via competitive DNA binding in Streptococcus pyogenes.
Not available
S-EPMC3509411 | biostudies-literature
UnknownPlastic roles of phenylalanine and tyrosine residues of TLS/FUS in complex formation with the G-quadruplexes of telomeric DNA and TERRA.
Not available
S-EPMC5809584 | biostudies-literature
UnknownTwo group A streptococcal peptide pheromones act through opposing Rgg regulators to control biofilm development.
Not available
S-EPMC3150281 | biostudies-literature
UnknownIdentifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model.
Not available
S-EPMC10841832 | biostudies-literature
UnknownThe <i>Streptococcus pyogenes</i> Rgg2/Rgg3 quorum sensing system causes global suppression of macrophage inflammatory programs via an intranuclear mechanism.
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S-EPMC12607563 | biostudies-literature
UnknownPptAB Exports Rgg Quorum-Sensing Peptides in Streptococcus.
Not available
S-EPMC5167397 | biostudies-literature
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