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TranscriptomicsGeneration of Naïve Induced Pluripotent Stem Cells from Rhesus Monkey Fibroblasts
Conventional embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) derived from primates resemble mouse epiblast stem cells, raising an intriguing question regarding whether the naïve pluripotent state resembling mouse embryonic stem cells (mESCs) exists in primates and how to captur...
ORGANISM(S): Macaca mulatta 
2014-10-14 | E-GEOD-61420 | biostudies-arrayexpress
TranscriptomicsJoint analysis of microRNome and 3'-UTRome in the endometrium of rhesus monkey
Here we used rhesus monkey as an animal model and compared the endometrial miRNA expression profiles during early-secretory (day 15, pre-receptive) phase and mid-secretory (day 21, receptive) phase by deep sequencing. In order to facilitate the prediction of their target genes, the 3'-UTRome was als...
ORGANISM(S): Macaca mulatta 
2011-07-30 | E-GEOD-31041 | biostudies-arrayexpress
TranscriptomicsTranscriptome study in rhesus monkey
Rhesus Monkey is one of the important primate models widely used in the fields of disease mechanism study, pre-clinical test in drug discovery and molecular evolution. However, the majority of rhesus gene annotations were putatively mapped from human genome, with only 10% supported by rhesus EST dat...
ORGANISM(S): Macaca mulatta 
2012-10-10 | E-GEOD-34426 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq and microRNA-Seq whole-transcriptome analysis of rhesus monkey ESC neural differentiation revealed the potential rosette neural stem cell regulators
Rosette neural stem cells (R-NSCs) represent early stage of neural development and possess full neural differentiation and regionalization capacities. R-NSCs are considered as stem cells of neural lineage and have important implications in study of neurogenesis and cell replacement therapy. However,...
ORGANISM(S): Macaca mulatta 
2014-07-03 | E-GEOD-53260 | biostudies-arrayexpress
OtherA draft map of rhesus monkey tissue proteome for biomedical research.
Data from ProteomeXchange, PXD ID: PXD001972. Experiment: male, file: MALE_PROSTATE_MID.msf.mgf. Published as part of PLoS One. 2015 May 14;10(5):e0126243 . From the Abstract: {{i}} Though the rhesus monkey is one of the most valuable non-human primate animal models for various human diseases becau...
ORGANISM(S): Homo_sapiens_viruses, Rhesus_monkey_papillomavirus_1_uid14025, Rhesus 
GPM32310019946 | GPMDB
Resource Reanalysis 
TranscriptomicsGeneration of Induced Pluripotent Stem Cells from Adult Rhesus Monkey Fibroblasts
Induced pluripotent stem (iPS) cells can be generated from somatic cells by transduction with several transcription factors in both mouse and human. However, direct reprogramming in other species has not been reported. Here, we established an efficient method to generate monkey iPS cells from fibrob...
ORGANISM(S): Macaca mulatta 
2010-05-15 | E-GEOD-13146 | biostudies-arrayexpress
TranscriptomicsExtensive effects of in vitro oocyte maturation on rhesus monkey cumulus cell transcriptome
The elaboration of a quality oocyte is integrally linked to the correct developmental progression of cumulus cell phenotype. In humans and non-human primates, oocyte quality is diminished with in vitro maturation. To determine the changes in gene expression in rhesus monkey cumulus cells (CC) that o...
ORGANISM(S): Macaca mulatta 
2011-05-22 | E-GEOD-25288 | biostudies-arrayexpress
TranscriptomicsX-chromosome inactivation in monkey embryos and pluripotent stem cells
In this study, we explored x-inactivation in monkey embryos (ICM and TE separately) and pluripotent stem cells (IVF derived ES, SCNT-derived ES and monkey iPS) To elucidate x-inactivation in experimentally reprogrammed pluripotent cells, we derived pluripotent stem cells by both SCNT and iPS approac...
ORGANISM(S): Macaca mulatta 
2012-08-31 | E-GEOD-36252 | biostudies-arrayexpress
TranscriptomicsDerivation of Rhesus Monkey Parthenogenetic Embryonic Stem Cells and its MicroRNA Signature
We derived two novel rpESC lines and characterized their microRNA signature by Solexa deep sequencing. By characterizing their microRNA signature, we identified 91 novel microRNAs, except those are also detected in other primate ESCs. Moreover, these two novel rpESCs display a unique microRNA signat...
ORGANISM(S): Macaca mulatta 
2011-10-18 | E-GEOD-30510 | biostudies-arrayexpress
TranscriptomicsExpression data from 5 rhesus tissues at 3 centers
Novel approaches were used to generate the DNA sequence information for the rhesus GeneChip (2005). The purpose of this experiment was to test its reliability and validity of the rhesus macaque GeneChip across different tissues and centers. Keywords: reliability To test the reliability of the rhesus...
ORGANISM(S): Macaca mulatta 
2010-06-11 | E-GEOD-7094 | biostudies-arrayexpress
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