Sort   by:  
 Page size 
ProteomicsRhoBTB1 C-Terminal Binding Proteins in A7r5 Smooth Muscle Cells
The RhoBTB1-Cullin3 (CUL3) pathway in smooth muscle cells (SMCs) controls the ubiquitination of target proteins and through this blood pressure (BP) and arterial stiffness. We performed APEX2 proximity labelling coupled with mass spectrometry to identify RhoBTB1 interacting partners in A7R5 SMCs. We...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-04-06 | PXD067797 | Pride
Proximity ligation Rhobtb1 Apex2 
ProteomicsRhoBTB1 Binding Proteins in Placenta Detected by APEX2
We used RhoBTB1-APEX2 fusion protein specifically employing the C-terminal half of RhoBTB1 (termed B1B2C) to detect binding proteins in HTR8/SVneo cells, a trophoblast cell line.
ORGANISM(S): Homo sapiens (Human) 
2026-08-13 | PXD073804 | Pride
Rhobtb1 Placenta Apex2 Htr8 
GenomicsRhoBTB1 Reverses Established Arterial Stiffness in Angiotensin II Hypertension
RhoBTB1 Reverses Established Arterial Stiffness in Angiotensin II Hypertension
PRJNA781123 | ENA
ProteomicsRhoBTB1 C-Terminal Binding Proteins
We identified Rho Related BTB Domain Containing 1 (RhoBTB1) as a key regulator of phosphodiesterase 5 (PDE5) activity, and through PDE5, a regulator of vascular tone. We identified the binding interface for PDE5 on RhoBTB1 by truncating full-length RhoBTB1 into its component domains. Co-immunoprecip...
ORGANISM(S): Homo sapiens (Human) 
2023-08-21 | PXD043245 | Pride
Mass spec Proteomics Protein:protein interactions 
TranscriptomicsRhoBTB1 Reverses Established Arterial Stiffness in Angiotensin II Hypertension
We are investigating of role of RhoBTB1 in vascular smooth muscle cells. Restoring RhoBTB1 expression in mouse aorta reversed the established arterial stiffness but not hypertension caused by angiotensin II (Ang-II). To investigate the underlying mechanism by which RhoBTB1 reversed arterial stiffnes...
ORGANISM(S): Mus musculus 
2022-04-08 | GSE189003 | GEO
UnknownRhoBTB1 interacts with ROCKs and inhibits invasion.
Not available
S-EPMC6744581 | biostudies-literature
TranscriptomicsRbFox2 is a RhoBTB1-Cullin-3 Target in Vascular Smooth Muscle Regulating Arterial Stiffness through the Cytoskeleton
The RhoBTB1-Cullin3 (CUL3) pathway in smooth muscle cells (SMCs) controls the ubiquitination of target proteins and through this blood pressure (BP) and arterial stiffness. We performed proximity labelling coupled with mass spectrometry to identify RhoBTB1 interacting partners in A7R5 SMCs. We ident...
ORGANISM(S): Rattus norvegicus 
2026-03-24 | GSE305901 | GEO
GenomicsRbFox2 is a RhoBTB1-Cullin-3 Target in Vascular Smooth Muscle Regulating Arterial Stiffness through the Cytoskeleton
RbFox2 is a RhoBTB1-Cullin-3 Target in Vascular Smooth Muscle Regulating Arterial Stiffness through the Cytoskeleton
PRJNA1308147 | ENA
UnknownRhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity.
Not available
S-EPMC6546477 | biostudies-literature
UnknownStructure and Function of RhoBTB1 Required for Substrate Specificity and Cullin-3 Ubiquitination.
Not available
S-EPMC10413933 | biostudies-literature
Sort   by:  
 Page size