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TranscriptomicsSelf-organization of polarized cerebellar plate neuroepithelium in three-dimensional culture of human pluripotent stem cells
During cerebellar development, the main portion of the cerebellar plate neuroepithelium (NE) gives birth to Purkinje cells and interneurons, while the germinal zone at its dorsal edge, called the rhombic lip (RL), generates granule cells and cerebellar nuclei neurons. However, it remains elusive how...
ORGANISM(S): Homo sapiens 
2015-04-15 | E-GEOD-63015 | biostudies-arrayexpress
UnknownWls provides a new compartmental view of the rhombic lip in mouse cerebellar development.
Not available
S-EPMC4160781 | biostudies-literature
UnknownEvidence of disrupted rhombic lip development in the pathogenesis of Dandy-Walker malformation.
Not available
S-EPMC8544025 | biostudies-literature
GenomicsUnified rhombic lip origins of Group 3 and Group 4 medulloblastoma [methylation]
Unified rhombic lip origins of Group 3 and Group 4 medulloblastoma [methylation]
PRJNA862942 | ENA
UnknownUnified rhombic lip origins of group 3 and group 4 medulloblastoma.
Not available
S-EPMC9748853 | biostudies-literature
GenomicsFailure of human rhombic lip differentiation constitutes medulloblastoma
Failure of human rhombic lip differentiation constitutes medulloblastoma
PRJNA826820 | ENA
UnknownNetrin-1 Confines Rhombic Lip-Derived Neurons to the CNS.
Not available
S-EPMC5877811 | biostudies-literature
UnknownZIC1 is a context-dependent medulloblastoma driver in the rhombic lip.
Not available
S-EPMC11735403 | biostudies-literature
UnknownAntagonism between Notch and bone morphogenetic protein receptor signaling regulates neurogenesis in the cerebellar rhombic lip.
Not available
S-EPMC1820780 | biostudies-literature
TranscriptomicsNovel mutations target distinct subgroups of medulloblastoma.
Medulloblastoma is a malignant childhood brain tumour comprising four discrete subgroups. To identify mutations that drive medulloblastoma we sequenced the entire genomes of 37 tumours and matched normal blood. One hundred and thirty-six genes harbouring somatic mutations in this discovery set wer...
ORGANISM(S): Homo sapiens 
2012-07-05 | E-GEOD-37418 | biostudies-arrayexpress
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