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Transcriptional profiling of ribociclib-treated sensitive and ribociclib resistant CAMA-1 cells
Do illuminate the vulnerabilities of CDK4/6i-resistant T47D breast cancer cells, we created CDK4/6i-resistant T47D cell clones through a gradual dose escalation protocol using the selective CDK4/6 inhibitors Ribociclib and Palbociclib. We then performed gene expression analysis targeting 2549 genes ...
ORGANISM(S): Homo sapiens 
Effect of ribociclib on breast cancer cells
We report transcriptional response to ribociclib treatment in resistant and sensitive CAMA-1 cells using RNA sequencing. Acquired ribociclib resistant cells were generated by treating CAMA-1 cells over a period of 5 month. Cells were then treated with ribociclib or DMSO control and processed for RNA...
ORGANISM(S): Homo sapiens 
2020-06-22 | GSE143944 | GEO
To study mechanisms underlying response to ribociclib.
ORGANISM(S): Homo sapiens 
2022-01-10 | GSE182288 | GEO
Single-cell RNA-sequencing of Ribociclib treated mTECs
Pharmacokinetics and Pharmacogenomics of Ribociclib in Race-based Cohorts (LEANORA)
Pharmacokinetics and Pharmacogenomics of Ribociclib in Race-based Cohorts (LEANORA)
Ribociclib Derivative RB-BC Induces Apoptosis in Breast Cancer through p53 Pathway Activation
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