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A transgenic line cmlc2:TRAP was made to express EGFP-fused ribosomal protein L10a (EGFP-L10a) in zebrafish cardiomyocytes. Then ribosome-associated RNAs were immuoprecipitated from uninjured and injured adult cmlc2:TRAP fish to determine the differential expression changes during zebrafish heart re...
ORGANISM(S): Danio rerio 
Identification of translating small open reading frames (sORFs) through deep sequecing of ribosome-associated poly-adenylated RNA and conservation analysis in early Drosophila embryo
ORGANISM(S): Drosophila melanogaster 
Nascent polypeptides emerging from the ribosome during biogenesis can interact with many chaperones and protein homeostasis factors. The high sensitivity of RNA identification can be used to identify substrates of specific cotranslationally acting chaperones. Protein A-tagged (TAP-tag) chaperones as...
ORGANISM(S): Saccharomyces cerevisiae 
Diamond Blackfan anemia is a congenital bone marrow failure syndrome characterized by hypoproliferative anemia, often with associated physical abnormalities. Perturbations of the ribosome appear critically important to the development of DBA, as alterations in 9 different ribosomal protein genes ha...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
Data from ProteomeXchange, PXD ID: PXD001406. Experiment: GM19138, MSB14233, file: GM19138_MSB14233_29.mzml. Published as part of Science 2014 Dec. 18 . From the Abstract: {{i}} ... we mapped genetic variants that are associated with eQTLs, ribosome occupancy (rQTLs), or protein abundance (pQTLs). ...
ORGANISM(S): Homo_sapiens_viruses, Human 
Data from ProteomeXchange, PXD ID: PXD001406. Experiment: GM18519, MSB14195, file: GM18519_MSB14195_16.mzml. Published as part of Science 2014 Dec. 18 . From the Abstract: {{i}} ... we mapped genetic variants that are associated with eQTLs, ribosome occupancy (rQTLs), or protein abundance (pQTLs). ...
ORGANISM(S): Homo_sapiens_viruses, Human 
Osteoarthritis is a chronic disease characterised by the loss of articular cartilage in synovial joints through a process of extracellular matrix destruction that is strongly associated with inflammatory stimuli. Chondrocytes undergo changes to their protein translation capacity during osteoarthriti...
ORGANISM(S): Homo sapiens 
Study of ribosome dynamics of rpl3[W255C] and its interactions with ribosome-associated chaperones
Analysis of gene expression by astrocytes or non-astrocyte cells in spinal cord injury (SCI) lesions may lead to the identification of molecules that impact on axon regrowth. We conducted genome-wide RNA sequencing of (i) immunoprecipitated astrocyte-specific ribosome-associated RNA (ramRNA) from WT...
ORGANISM(S): Mus musculus 
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