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TranscriptomicsTranscription profiling of Drosophila CA/AA time series of y w
Circadian clocks are temporally aligned to the environment via signals, or Zeitgebers, such as daily light and temperature cycles, food availability, and social behavior. In this study, we show that genome-wide expression profiles from temperature-entrained flies show a dramatic difference in the pr...
ORGANISM(S): Drosophila melanogaster 
2008-06-14 | E-GEOD-6490 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila CA/AA time series of y w tim01
Circadian clocks are temporally aligned to the environment via signals, or Zeitgebers, such as daily light and temperature cycles, food availability, and social behavior. In this study, we show that genome-wide expression profiles from temperature-entrained flies show a dramatic difference in the pr...
ORGANISM(S): Drosophila melanogaster 
2008-06-14 | E-GEOD-6493 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila second CA/AA time series of y w
Circadian clocks are temporally aligned to the environment via signals, or Zeitgebers, such as daily light and temperature cycles, food availability, and social behavior. In this study, we show that genome-wide expression profiles from temperature-entrained flies show a dramatic difference in the pr...
ORGANISM(S): Drosophila melanogaster 
2008-06-14 | E-GEOD-6491 | biostudies-arrayexpress
TranscriptomicsM. sedula transcriptional response under "strict" carbon-limited autotrophy compared to carbon "rich" autotrophy and heterotrophy
Metallosphaera sedula is an extremely thermoacidophilic archaeon that grows heterotrophically on peptides, and chemolithoautotrophically on hydrogen, sulfur, or reduced metals as energy sources. During autotrophic growth, carbon dioxide is incorporated into cellular carbon via the 3-hydroxypropionat...
ORGANISM(S): Metallosphaera sedula DSM 5348 
2013-03-05 | E-GEOD-39944 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human epithelium-only colonic and small intestinal organoids derived from intestinal resections, biopsy specimens and cryopreserved crypts
Patient-derived gastrointestinal epithelium-only organoids from the small and large intestine, also referred to as colonoids and enteroids, were generated as part of the development of an on-going organoid biobank at the Michigan Medicine Translational Tissue Modeling Laboratory (TTML) (www.UmichTTM...
ORGANISM(S): Homo sapiens 
2020-07-24 | E-MTAB-9339 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli K-12 W3110 strain grown at Ph5.7, 7.0, 8.5 reveals pH and anaerobiosis coregulate metabolism, multidrug transporters, and envelope composition
In Escherichia coli, pH-dependent gene expression varies with oxygen level. Anaerobic pH-dependent expression ratios were analyzed and compared to the published analysis of aerated cultures (Maurer et al, 2005). E. coli K-12 strain W3110 was cultured in closed tubes containing LBK broth buffered a...
ORGANISM(S): Escherichia coli 
2008-06-13 | E-GEOD-4556 | biostudies-arrayexpress
GenomicsTranscriptional and Epigenetic Dynamics During Specification of Human Embryonic Stem Cells
Differentiation of human embryonic stem cells (hESCs) provides a unique opportunity to study the epigenetic mechanisms that facilitate cellular transitions in a human context. To that end, we performed comprehensive transcriptional and epigenetic profiling of early populations derived through direct...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-46130 | biostudies-arrayexpress
GenomicsGenomic Analysis of Pediatric Low Grade Gliomas

Pediatric low-grade gliomas (PLGGs) are among the most common solid tumors in children but, apart from mutations or duplications in the BRAF kinase in specific subclasses, few genetic driver events are known. Diffuse PLGGs compose a set of uncommon subtypes that exhibit invasive growth and are th...

phs000614.v1.p1 | EGA
GenomicsA molecular shift in limb identity underlies the convergent evolution and development of feathered feet
The genetic and developmental mechanisms that control the decision between scale and feather growth – two profoundly different epidermal appendages, and an important developmental shift in the evolution of birds from their dinosaurian ancestors – remain poorly understood. Domestic pigeons displa...
ORGANISM(S): Columba livia 
2016-04-03 | E-GEOD-67875 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of hPSC-derived human intestinal organoids with endogenous vascular endothelial cells
The development of human pluripotent stem cell (hPSC)- derived small intestinal organoids (HIOs) has led to an improved understanding of human intestinal development and physiology. HIOs generated using directed differentiation lack some cellular populations found in the native organ, including vasc...
ORGANISM(S): Homo sapiens 
2020-12-20 | E-MTAB-9228 | biostudies-arrayexpress
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