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TranscriptomicsSingle-cell RNA sequencing of OT-I CD8+ T cells after stimulation with different affinity ligands
Activation of CD8+ T cells depends exquisitely on the affinity of the T cell receptor (TCR) for a peptide MHC (pMHC) ligand complex. Here, we activated OT-I transgenic CD8+ T cells with pure peptide and examined early activation responses by single-cell RNA-sequencing. T cells were activated with th...
ORGANISM(S): Mus musculus 
2018-06-25 | E-MTAB-6051 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of peripheral blood leukocyte subsets in autoimmune/autoinflammatory disease patients and healthy controls
Gene expression microarray profiling was performed on peripheral blood leukocyte subsets (CD4+ T cells, CD14+ monocytes, and CD16+ neutrophils) from healthy controls and patients with flaring autoimmune disease.
ORGANISM(S): Homo sapiens 
2014-08-31 | E-MTAB-2452 | biostudies-arrayexpress
GenomicsIlluminaHumanDT - samples
Genotyping using Illumina Human OmniExpress12v1.0
EGAD00010000748 | EGA
GenomicsLeucocyte eQTLs in autoimmune disease and health
Peripheral blood was taken from healthy controls and patients with active autoimmune disease. CD4 T cells, CD8 T cells, monocytes, neutrophils, and B cells were separated using magnetic-activated cell sorting. RNA and genomic DNA was extracted from cell lysates using Qiagen Allprep kits. Genotyping ...
EGAS00001001251 | EGA
GenomicsLeucocyte eQTLs in autoimmune disease and health
Data Access Committee EGAC00001000338
EGAC00001000338 | EGA
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