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UnknownClinical effectiveness of the Circle of Security-Parenting group intervention for birthing parents in perinatal mental health services in England (COSI): a pragmatic, multicentre, assessor-masked, randomised controlled trial.
Not available
S-EPMC12521337 | biostudies-literature
TranscriptomicsGene expression and genotype in normal heart
Genome-wide association studies have identified a small region at chromosome 9p21.3 strongly associated with coronary heart disease risk. The region contains no protein-coding genes and the mechanism underlying its association with heart disease is unknown. We investigated associations between rs133...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-22253 | biostudies-arrayexpress
TranscriptomicsA Phase Two Randomised Controlled Trial of Belimumab in Kidney Transplant Recipients Demonstrates Comparable Safety, a Reduction in De Novo Antibody Production and an Increase in Regulatory B Cells.
There is an urgent unmet need in solid organ transplantation for immunotherapeutic strategies that target B cells and plasma cells, ideally without increasing infectious complications. We conducted a phase 2 double-blind randomised placebo-controlled trial to assess the safety and potential efficacy...
ORGANISM(S): Homo sapiens 
2018-06-11 | E-MTAB-5906 | biostudies-arrayexpress
UnknownThe COSI trial: a study protocol for a multi-centre, randomised controlled trial to explore the clinical and cost-effectiveness of the Circle of Security-Parenting Intervention in community perinatal mental health services in England.
Not available
S-EPMC10012495 | biostudies-literature
UnknownTrial protocol for the Building Resilience through Socio-Emotional Training (ReSET) programme: a cluster randomised controlled trial of a new transdiagnostic preventative intervention for adolescents.
Not available
S-EPMC10885387 | biostudies-literature
ProteomicsMolecular and metabolites regulation in response to Juvenile hormone treatment on Eurasian spruce bark beetle: Ips typographus.
The Eurasian spruce bark beetle Ips typographus is known for its devasting attack on the host tree Picea abies, a common conifer in Europe. The beetle uses various pheromone components (2-methyl-3-buten-2-ol and cis-verbenol) for mass aggregation to overcome the tree defence compounds such as terpen...
ORGANISM(S): Ips typographus 
2024-01-22 | PXD039243 | Pride
Ips typographus Picea abies 
UnknownCost-utility analysis of the Circle of Security-Parenting programme to reduce perinatal psychopathology in birthing parents in England.
Not available
S-EPMC12931550 | biostudies-literature
TranscriptomicsGenetic, functional and molecular features of glucocorticoid receptor binding (expression)
Glucocorticoids (GCs) are key mediators of stress response and are widely used as pharmacological agents to treat immune diseases, such as asthma and inflammatory bowel disease, and certain types of cancer. GCs act mainly by activating the GC receptor (GR), which interacts with other transcription f...
ORGANISM(S): Homo sapiens 
2013-04-01 | E-GEOD-44248 | biostudies-arrayexpress
GenomicsGenetic, functional and molecular features of glucocorticoid receptor binding (sequencing)
Glucocorticoids (GCs) are key mediators of stress response and are widely used as pharmacological agents to treat immune diseases, such as asthma and inflammatory bowel disease, and certain types of cancer. GCs act mainly by activating the GC receptor (GR), which interacts with other transcription f...
ORGANISM(S): Homo sapiens 
2013-04-01 | E-GEOD-45638 | biostudies-arrayexpress
TranscriptomicsInteractions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes
Glucocorticoids (GCs) are steroid hormones produced by the human body in response to environmental stressors. Despite their key role as physiological regulators and widely administered pharmaceuticals, little is known about the genetic basis of inter-individual and inter-ethnic variation in GC respo...
ORGANISM(S): Homo sapiens 
2011-08-17 | E-GEOD-29342 | biostudies-arrayexpress
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