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TranscriptomicsRichards H. pylori stress treatments
To understand the survival of dormant, nonculturable H. pylori, we investigated changes in cell morphology and gene transcription associated with the loss in culturability seen under oxygen stress and nutrient deprivation. This study examined the gene transcription profiles associated with the trans...
ORGANISM(S): Helicobacter pylori 
2011-12-18 | E-MEXP-3376 | biostudies-arrayexpress
UnknownInositol 1,4,5-trisphosphate directs Ca(2+) flow between mitochondria and the Endoplasmic/Sarcoplasmic reticulum: a role in regulating cardiac autonomic Ca(2+) spiking.
Not available
S-EPMC14888 | biostudies-literature
TranscriptomicsCCAAT/Enhancer Binding Proteins (C/EBP)-M-NM-1 and -M-NM-2 are Essential for Ovulation, Luteinization and the Expression of Key Target Genes
Luteinizing hormone (LH) activation of the EGF receptor/RAS/ERK1/2 pathway is essential for ovulation and luteinization because granulosa cell depletion of Erk1/2 (Erk1/2gc-/- mice) renders mice completely infertile. Because of their potential as mediators of ERK1/2-dependent granulosa cell differe...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-23084 | biostudies-arrayexpress
TranscriptomicsERK1/2 in Ovarian Granulosa Cells are Essential for Female Fertility
A surge of luteinizing hormone (LH) from the pituitary gland triggers ovulation, oocyte maturation, and luteinization for successful reproduction in mammals. Since the signaling molecules RAS and ERK1/2 are activated by a LH surge in granulosa cells of preovulatory follicles, we disrupted Erk1/2 in ...
ORGANISM(S): Mus musculus 
2009-03-20 | E-GEOD-15315 | biostudies-arrayexpress
UnknownPointBreak: a randomized phase III study of pemetrexed plus carboplatin and bevacizumab followed by maintenance pemetrexed and bevacizumab versus paclitaxel plus carboplatin and bevacizumab followed by maintenance bevacizumab in patients with stage IIIB or IV nonsquamous non-small-cell lung cancer.
Not available
S-EPMC4881367 | biostudies-literature
UnknownUncovering the chemistry of C-C bond formation in C-nucleoside biosynthesis: crystal structure of a C-glycoside synthase/PRPP complex.
Not available
S-EPMC8183095 | biostudies-literature
TranscriptomicsTumor repressor protein 53 and steroid hormones provide a new paradigm for ovarian cancer metastases
The functional status of the tumor repressor protein (TP53 or TRP53) is a defining feature of ovarian cancer. Mutant or null alleles of TP53 are expressed in greater than 90% of all high-grade serous adenocarcinomas. Wild type TP53 is elevated in low-grade serous adenocarcinomas in women and in our ...
ORGANISM(S): Mus musculus 
2014-03-21 | E-GEOD-51095 | biostudies-arrayexpress
TranscriptomicsEffects of diet and Acads genotype on transcriptional response in brain and liver
How signals from fatty acid metabolism are translated into changes in food intake remains unclear. Previously we reported that mice with a genetic inactivation of Acads (short-chain acyl-CoA dehydrogenase), encoding the enzyme responsible for mitochondrial beta-oxidation of C4-C6 short-chain fatty ...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-35180 | biostudies-arrayexpress
UnknownGeneralized Born model with a simple, robust molecular volume correction.
Not available
S-EPMC2975579 | biostudies-literature
TranscriptomicsDifferential gene expression in hypothalamus of non-recombinant subcongenic-derived F2 mice fed macronutrient selection diets
The specific genes influencing the quantitative variation in macronutrient preference and food intake are virtually unknown. We refined a previously identified mouse chromosome 17 (MMU17) region harboring quantitative trait loci (QTL) with large effects on preferential macronutrient intake-carbohyd...
ORGANISM(S): Mus musculus 
2015-05-15 | E-GEOD-60756 | biostudies-arrayexpress
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