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MetabolomicsDiagnostic utility of clinicodemographic, biochemical and metabolite variables to identify viable pregnancies in a symptomatic cohort during early gestation.

Study question: Can a novel machine learning pipeline create predictive models that identify a composite biomarker to differentiate live normally sited pregnancies (LNSP) from non-viable pregnancies in women presenting with pain and/or bleeding in early gestation?

Summary answer: Serum met...

2025-08-14 | MTBLS6219 | MetaboLights
MetabolomicsA metabolomics dataset of plankton exometabolomes and dissolved organic compounds in the South Atlantic Ocean

The marine microbiome contributes to nearly half of our planet’s net primary production. It plays a central role in the ocean’s carbon cycle through both passive and active release of metabolites into seawater, forming a pool of dissolved compounds known as the marine exometabolome.


2026-05-19 | MTBLS14508 | MetaboLights
GenomicsMulti-omics of Richter syndrome
Richter syndrome (RS) is the aggressive transformation of Chronic Lymphocytic Leukemia, mostly with Diffuse Large B-Cell Lymphoma histology. While histologically similar, RS and de novo DLBCLs present with different clinical courses. We characterized the RS epigenome by combining genome-wide DNA met...
EGAS00001005495 | EGA
TranscriptomicsGenomic profiling of Richter-syndrome Chronic Lymphocytic Leukemia
Richter syndrome (RS) occurs in up to 15% of patients with chronic lymphocytic leukemia (CLL). While RS, usually represented by the histologic transformation to a diffuse large B-cell lymphoma (DLBCL), is associated with a very poor outcome, especially when clonally related to the pre-existing CLL, ...
ORGANISM(S): Homo sapiens 
2013-09-20 | E-GEOD-50252 | biostudies-arrayexpress
TranscriptomicsComparison of CLL and MCL primary cells obtained from a patient with MCL variant Richter syndrome
Comparison of CLL and MCL primary cells obtained from a patient with MCL variant Richter syndrome
ORGANISM(S): Homo sapiens 
2016-07-13 | GSE84286 | GEO
TranscriptomicsPRC2 in Ewing tumors
We found the PRC2 component EZH2 to be upregulated by the pathognomonic fusion oncogene EWS-FLI1 in Ewing tumors and mesenchymal stem cells (Richter GH et al., Proc Natl Acad Sci U S A. 2009;106:5324-9). Downregulation of EZH2 by RNA interference in Ewing tumor cell lines suppressed oncogenic transf...
ORGANISM(S): Homo sapiens 
2009-04-29 | E-GEOD-15757 | biostudies-arrayexpress
GenomicsOligoclonal T-cell expansion in a patient with bone marrow failure after CD19 CAR-T for Richter transformed DLBCL
Oligoclonal T-cell expansion in a patient with bone marrow failure after CD19 CAR-T for Richter transformed DLBCL
PRJNA832706 | ENA
UnknownEfficacy and safety of RGB-02, a pegfilgrastim biosimilar to prevent chemotherapy-induced neutropenia: results of a randomized, double-blind phase III clinical study vs. reference pegfilgrastim in patients with breast cancer receiving chemotherapy.
Not available
S-EPMC6364429 | biostudies-literature
UnknownThe involvement of microRNA in the pathogenesis of Richter syndrome.
Not available
S-EPMC6518906 | biostudies-literature
UnknownCariprazine, A Broad-Spectrum Antipsychotic for the Treatment of Schizophrenia: Pharmacology, Efficacy, and Safety.
Not available
S-EPMC8279990 | biostudies-literature
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