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ProteomicsThe proteome of Rickettsia akari revealed a 44kDa-OMP as novel biomarker for Rickettsialpox
Our study aimed to investigate the proteome structure of R. akari and unveil immunoreactive surface-exposed proteins using the latest proteomics techniques. To achieve these goals, we applied the Shotgun protein identification approach; membrane surface protein enrichment methods combined with liqui...
ORGANISM(S): Rickettsia akari 
2020-07-13 | PXD017762 | Pride
Egg culture Q-exactive Vero cell line Rickettsia akari 
MetabolomicsA metabolic dependency for host isoprenoids in the obligate intracellular pathogen Rickettsia parkeri underlies a sensitivity for the statin class of host-targeted therapeutics
Gram-negative bacteria in the order Rickettsiales are obligate intracellular parasites that cause human diseases such typhus and spotted fever. They have evolved a dependence on essential nutrients and metabolites from the host cell as a consequence of extensive genome streamlining. However, it rema...
2019-10-31 | MTBLS846 | MetaboLights
ProteomicsRickettsia akari: the proteome revealed a 44kDa-OMP as novel biomarker for Rickettsialpox
We identified 296 unique proteins separated by shotgun proteomics technique, 30 surface exposed proteins using biotinylation and 67 proteins by Triton X-114 detergent phase partitioning. Combination of different separation techniques with divers in silico analyses revealed 25 possibly beta-barrel ou...
ORGANISM(S): Rickettsia akari 
2021-09-09 | PXD018060 | Pride
Rickettsia akari Outer membrane proteins Liquid chromatography mass spectrometry 
GenomicsRickettsia akari str. Hartford
Causes Rickettsialpox disease
PRJNA12953 | ENA
GenomicsRickettsia akari
Causative agent of Rickettsialpox
PRJNA35393 | ENA
UnknownProteomic analysis of Rickettsia akari proposes a 44 kDa-OMP as a potential biomarker for Rickettsialpox diagnosis.
Not available
S-EPMC7341715 | biostudies-literature
GenomicsRickettsia akari str. Toger
Sequencing Rickettsiales Genomes
PRJNA212459 | ENA
GenomicsRickettsia akari str. Croatia
Sequencing Rickettsiales Genomes
PRJNA212469 | ENA
GenomicsRickettsia akari str. AS4-1
Sequencing Rickettsiales Genomes
PRJNA212470 | ENA
UnknownTranscription of the Rickettsia felis ompA gene in naturally infected fleas.
Not available
S-EPMC1440719 | biostudies-literature
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