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TranscriptomicsMYC is a major determinant of mitotic cell fate
Purpose: To determine global gene expression changes following siRNA knockdown of Myc, Kcnk1, and Snta1 compared to non-targeting siRNAs or mock-transfected cells Methods: Total RNA was processed using the Illumina TruSeq Stranded mRNA Sample Preparation Kit according to manufacturer’s protocol. Gen...
ORGANISM(S): Homo sapiens 
2015-07-13 | E-GEOD-68219 | biostudies-arrayexpress
UnknownSOX2 confers tumour permissiveness in a specific skin progenitor population.
Not available
S-EPMC12789432 | biostudies-literature
UnknownMmCMS: mouse models' consensus molecular subtypes of colorectal cancer.
Not available
S-EPMC10050155 | biostudies-literature
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
UnknownEndogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo.
Not available
S-EPMC4013513 | biostudies-literature
UnknownE-cadherin can limit the transforming properties of activating β-catenin mutations.
Not available
S-EPMC4570519 | biostudies-literature
MetabolomicsGNPS - Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | GNPS
UnknownEpithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.
Not available
S-EPMC6853173 | biostudies-literature
UnknownMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target.
Not available
S-EPMC10447251 | biostudies-literature
UnknownEpithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Not available
S-EPMC9729215 | biostudies-literature
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