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All cancers are diseases of the genome. A combination of somatic point mutations, focal amplifications and deletions, and chromosome level aberrations conspire to disrupt gene expression and the interplay between signaling pathways that control normal growth and tissue homeostasis. Here we investiga...
ORGANISM(S): Homo sapiens 
In the mammalian bloodstream, proliferative slender forms of T. brucei differentiate into cell cycle-arrested stumpy forms (stumpy-QS) via a quorum sensing mechanism triggered by high parasite density. This transition is thought to protect the host from excessive parasitaemia while preparing the par...
ORGANISM(S): Trypanosoma brucei 
2026-06-23 | PXD056405 | Pride
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