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TranscriptomicsRNA-seq of 7G8 cell bank parasites
The parasite Plasmodium falciparum is responsible for severe malaria, which remains a major cause of death, particularly in sub-Saharan Africa. The reference strain NF54 (or its subclone 3D7) is commonly used for controlled human malaria infection (CHMI), but recently strains with a different geogra...
ORGANISM(S): Plasmodium falciparum 7G8 
2022-09-22 | E-MTAB-12157 | biostudies-arrayexpress
UnknownA stereoselective synthesis of (-)-viridiofungin A utilizing a TiCl(4)-promoted asymmetric multicomponent reaction.
Not available
S-EPMC3262899 | biostudies-literature
TranscriptomicsCAR-adapted PIK3CD base editing enhances T cell anti-tumor potency
Insufficient functional T cell persistence impedes therapeutic success of chimeric antigen receptor (“CAR”) therapies. Here, we performed a CAR-adapted base editing screen of PIK3CD, a key regulator of T cell function, metabolism, and fate. We identified point mutations that beneficially modulate CA...
ORGANISM(S): Homo sapiens 
2025-11-06 | E-MTAB-15749 | biostudies-arrayexpress
UnknownRegulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.
Not available
S-EPMC4356340 | biostudies-literature
GenomicsgDNA-seq of 7G8 subclones with different var expression patterns
The parasite Plasmodium falciparum is responsible for severe malaria, which remains a major cause of death, particularly in sub-Saharan Africa. The reference strain NF54 (or its subclone 3D7) is commonly used for controlled human malaria infection (CHMI), but recently strains with a different geogra...
ORGANISM(S): Plasmodium falciparum 
2022-09-22 | E-MTAB-12158 | biostudies-arrayexpress
Transcriptomics3' single cell sequencing of CD45+ lymphocytes sorted from mesenteric white adipose tissue in wildtype C57BL/6 and WIPf1-/- mice
Mesenteric white adipose tissue from wildtype C57BL/6 and Wipf1-/- mice was harvested through vivosection, minced and digested. Tissue-resident lymphocytes were enriched with Percoll gradient centrifugation. CD45 staining and fluorescence associated cell sorting were performed to achieve a pure lymp...
ORGANISM(S): Mus musculus 
2026-07-31 | E-MTAB-17384 | biostudies-arrayexpress
TranscriptomicsInterleukin-1 signaling is involved in local self-renewal and maintenance of microglia
During early embryogenesis microglia arise from yolk sac progenitors populating the developing CNS, where they are maintained as tissue-resident macrophages throughout the organism’s lifespan. Here, we describe an experimental system that allows the specific conditional ablation of microglia in vivo...
ORGANISM(S): Mus musculus 
2015-07-15 | E-GEOD-68376 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in Daphnia magna, Part III: Uncovering Biomarkers for Metal and ORC exposures
To determine toxicant specific effects of Ordnance Related Compound (ORC) exposure we performed microarray hybridizations with RNA isolated from Daphnia magna following different ORC exposures at the 1/10 LC50. The gene expression profiles revealed toxicant specific gene expression profiles allowed...
ORGANISM(S): Daphnia magna 
2010-05-18 | E-GEOD-13169 | biostudies-arrayexpress
ProteomicsThe HLA-Ligand-Atlas. A resource of natural HLA ligands presented on benign tissues
The human leukocyte antigen (HLA) complex regulates the adaptive immune response by showcasing the intracellular and extracellular protein content to the immune system. T cells recognize these HLA-presented peptides as self or foreign and can elicit an immune response. In this work, we describe the...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-31 | MSV000096271 | MassIVE
UnknownThe HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity
Not available
S-SCDT-EMM-2021-13952 | biostudies-other
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