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RIPK4 but not the related kinases RIPK1, RIPK2, and RIPK3 caused similar transcriptional changes to Wnt3a. PA1 cells were transfected by 8ug RIPK1, RIPK2, RIPK3, or RIPK4 for 48h, RNA were extracted and sequenced.
ORGANISM(S): Homo sapiens 
RIPK4 in Osteolineage cells regulate bone and bone marrow homeostasis via MFN2
Human RIPK4 mutation leads to Bartsocas-Papas syndrome (BPS), characterized by severe craniofacial, skin and limb abnormalities. However, how RIPK4 regulates skeletal system development remains largely elusive. Herein, using global RIPK4 ablation mice model, we demonstrated that RIPK4 deficiency cau...
ORGANISM(S): Mus musculus 
2025-05-19 | GSE243610 | GEO
RIPK4 promotes oxidative stress and ferroptotic death through the downregulation of ACSM1
RNAseq E15.5 mouse skin WT, Irf6 KO, Ripk4 KD, and Irf6 S413A.S424A knockin
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