497362 Results

Show all   Save search   Copy query
Sort   by:  
 Page size 
TranscriptomicsMethylation profiling of Low-Risk Myelodysplastic Syndromes (MDSs)
Genome-wide expression and methylation profiling identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes (MDSs). Gene expression profiling signatures may be used to classify the subtypes of Myelodysplastic syndrome (MDS) patients. However,...
ORGANISM(S): Homo sapiens 
2012-09-28 | E-GEOD-41215 | biostudies-arrayexpress
ProteomicsMetabolic reprogramming in the airway epithelium of high risk individuals
We investigated proteins identified by shotgun proteomics in cytologically normal airway epithelial cells from individuals at different levels of risk for lung cancer. We identified 2869 proteins in bronchial brushings from individuals at low, moderate or high risk for lung cancer. Pathway analysis ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000079331 | MassIVE
TranscriptomicsGenome-wide profiling of methylation identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes.
This SuperSeries is composed of the following subset Series: GSE41130: Expression profiling of Low-Risk Myelodysplastic Syndromes (MDSs) GSE41215: Methylation profiling of Low-Risk Myelodysplastic Syndromes (MDSs) Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-09-28 | E-GEOD-41216 | biostudies-arrayexpress
TranscriptomicsBreastPRS is a Gene Expression Assay that Stratifies Intermediate-Risk Oncotype DX Patients into High or Low-Risk for Disease Recurrence
Molecular prognostic assays, such as Oncotype DX, are increasingly incorporated into the management of patients with invasive breast carcinoma. BreastPRS is a new molecular assay developed and validated from a meta-analysis of publically available genomic datasets. We applied the assay to matched fr...
ORGANISM(S): Homo sapiens 
2013-06-23 | E-GEOD-47109 | biostudies-arrayexpress
TranscriptomicsExpression data of Low-Risk Myelodysplastic Syndromes (MDSs)
Genome-wide expression and methylation profiling identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes (MDSs). Gene expression profiling signatures may be used to classify the subtypes of Myelodysplastic syndrome (MDS) patients. However,...
ORGANISM(S): Homo sapiens 
2012-09-25 | E-GEOD-41130 | biostudies-arrayexpress
GenomicsComprehensive Functional Annotation of 77 Prostate Cancer Risk Loci
Genome-wide association studies (GWAS) have revolutionized the field of cancer genetics, but the causal links between increased genetic risk and onset/progression of disease processes remain to be identified. Here we report the first step in such an endeavor for prostate cancer. We provide a compreh...
ORGANISM(S): Homo sapiens 
2014-01-28 | E-GEOD-51621 | biostudies-arrayexpress
TranscriptomicsExpression data of small intestine crypts and villi from mice with nutritional and genetic risk factors for intestinal tumors
Nutritional and genetic risk factors for intestinal tumors are additive on mouse tumor phenotypes, demonstrating that diet and genetic factors impact risk by distinct combinatorial mechanisms. We analyzed expression profiles of small intestine crypts and villi from mice with nutritional and genetic ...
ORGANISM(S): Mus musculus 
2011-05-31 | E-GEOD-29538 | biostudies-arrayexpress
GenomicsComprehensive Functional Annotation of Seventy-One Breast Cancer Risk Loci
We report the application of FAIRE seq in Human Mammary Epithelial Cells for identifying the breast cancer risk functional SNPs in enhancer region. Examination of FAIRE assay in HMEC
ORGANISM(S): Homo sapiens 
2013-05-10 | E-GEOD-46074 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profiling in high-risk neuroblastoma
In the present study we evaluated the miRNA expression profile of 31 high risk, stage 4 neuroblastoma patients. We compared miRNA expression profiles of 14 long-survivors (alive with an overall survival time > 36 months) and 17 short-survivors (dead of disease within 36 months from diagnosis. Deaths...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-16444 | biostudies-arrayexpress
TranscriptomicsA Supervised Risk Predictor of Breast Cancer Based on Biological Subtypes
Purpose: The biological subtypes of breast cancer designated as Luminal A, Luminal B, HER2+/ER-, and Basal-like are clinically important for prognosis and planning treatment strategies. Recognizing that there is a continuum in both the spectrum of breast cancer disease and the risk of survival, we s...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-10886 | biostudies-arrayexpress
Sort   by:  
 Page size