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ProteomicsEffects of Iron Deficiency and Risperidone treatment on the rat frontal cortex
Prenatal iron deficiency (pID) has been described to increase the risk for neurodevelopmental disorders such as autism and schizophrenia; however, the precise molecular mechanisms are still unknown. Here, we utilized high throughput mass spectrometry to examine the proteomic effects of pID in adulth...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-07-05 | PXD004975 | Pride
Iron defiency Rat Risperidone Lc msms 
TranscriptomicsExpression data SK-N-SH cells treated with risperidone
We performed a pharmacotranscriptomic analysis of a human neuroblastoma cell line (SK-N-SH) exposed to risperidone to identify molecular mechanisms involved in the cellular response to risperidone and thus identify candidate genes for pharmacogenetic studies. This study is a part of a convergent fu...
ORGANISM(S): Homo sapiens 
2012-03-22 | E-GEOD-36678 | biostudies-arrayexpress
GenomicsDeciphering risperidone-induced lipogenesis by network pharmacology and molecular validation
Deciphering risperidone-induced lipogenesis by network pharmacology and molecular validation
PRJNA813537 | ENA
TranscriptomicsNetwork analysis of gene expression in mice provides new evidence of involvement of the mTOR pathway in antipsychotic-induced extrapyramidal symptoms
To identify potential candidate genes for future pharmacogenetic studies of antipsychotic (AP)-induced extrapyramidal symptoms (EPS), we used gene expression arrays to analyze changes induced by risperidone in mice strains with different susceptibility to EPS This study is a part of a convergent fun...
ORGANISM(S): Mus musculus 
2015-04-09 | E-GEOD-67723 | biostudies-arrayexpress
TranscriptomicsExpression data SK-N-SH cells treated with risperidone
We performed a pharmacotranscriptomic analysis of a human neuroblastoma cell line (SK-N-SH) exposed to risperidone to identify molecular mechanisms involved in the cellular response to risperidone and thus identify candidate genes for pharmacogenetic studies. This study is a part of a convergent fun...
ORGANISM(S): Homo sapiens 
2012-03-22 | GSE36678 | GEO
GenomicsLong-term effects of adolescent risperidone treatment on mouse cortex
Long-term effects of adolescent risperidone treatment on mouse cortex
PRJNA1400582 | ENA
GenomicsThe Atypical Antipsychotic Risperidone Targets Central Melanocortin 4 Receptors to Cause Weight
The Atypical Antipsychotic Risperidone Targets Central Melanocortin 4 Receptors to Cause Weight
PRJNA666420 | ENA
TranscriptomicsBlood methylomes of schizophrenia patients differing in their response to risperidone treatment
Schizophrenia patients vary in their response to antipsychotic (AP) treatment and predicting if and which therapy will be efficient is of high clinical and social importance. Here, we set out to analyze blood methylomes of 28 schizophrenia patients just before starting (baseline) risperidone treatme...
ORGANISM(S): Homo sapiens 
2023-03-19 | E-MTAB-11921 | biostudies-arrayexpress
TranscriptomicsDeciphering risperidone-induced lipogenesis by network pharmacology and molecular validation
Risperidone is an atypical antipsychotic that can cause substantial weight gain. The pharmacological targets and molecular mechanisms related to risperidone-induced lipogenesis (RIL) remain to be elucidated. Therefore, network pharmacology and further experimental validation were undertaken to explo...
ORGANISM(S): Mus musculus 
2022-05-11 | GSE198053 | GEO
GenomicsC6 glioblastoma microRNA regulation induced by haloperidol, risperidone and clozapine
C6 glioblastoma microRNA regulation induced by haloperidol, risperidone and clozapine
PRJNA533124 | ENA
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