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TranscriptomicsRNAi knock down of SIM2s in human RKO colon carcinoma cells in a timecourse
RKO Colon Carcinoma Cells were treated with 100nM of either SIM2s Control or Antisense oligos in a timecourse (10, 14, 18, 24hr) dependent manner.
ORGANISM(S): Homo sapiens 
2004-11-01 | E-MEXP-101 | biostudies-arrayexpress
TranscriptomicsExpression data from RKO cells transfected with SPARCL1 and vector control
Colon cancer cell line RKO grown on Matrigel form a luminal-like structure after the transfection of SPARCL1 gene, which may imply the differentiation of the cells. To indentify genes regulated by SPARCL1, we built two stable cell lines: RKO with pLXSN-SPARCL1 plasmid (RKO-SPARCL1) and RKO with pLXS...
ORGANISM(S): Homo sapiens 
2011-09-29 | E-GEOD-31440 | biostudies-arrayexpress
TranscriptomicsMethylation analysis of normal lymphocytes, HCT116, RKO and SW480
Methylation analysis of normal lymphocytes, HCT116, RKO and SW480 In vitro methylated DNA (IVD) generated from normal lymphocytes, HCT116, RKO and SW480 genomic DNA was subjected to sodium bisulfite treatment and the DNA was analyzed for CpG methylation using the Infinium Methylation Array.
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-50511 | biostudies-arrayexpress
TranscriptomicsExpression array of RKO colorectal cancer cells resistant to irinotecan (CPT-11)
RKO cells and irinotecan resistant derivatives (316 and 526) were compared for expression profile.
ORGANISM(S): Homo sapiens 
2017-06-17 | E-MTAB-5184 | biostudies-arrayexpress
TranscriptomicsDNMT3B targets in RKO cells by ChIP-on-chip
Chromatin immunoprecipitation with DNMT3B specific antibody followed by CGI microarray identified genes with or without CGIs, repeat elements and genomic contigs in RKO cells. ChIP-Chop analysis showed that majority of the target genes including P16, DCC, DISC1, SLIT1, CAVEOLIN1, TBX5, TBX18, HOXB1...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-18929 | biostudies-arrayexpress
TranscriptomicsExpression data after BCLAF1-L knockdown in human RKO cells
Bcl-2-accociated transcription factor 1(BCLAF1) has been reported to be involved in diverse biological processes. Alternative splicing leads to mutiple transcript virants in human cells and we are interested in functions of its full length isoform(BCLAF1-L) in human colon cancer cells, thus to under...
ORGANISM(S): Homo sapiens 
2013-12-05 | E-GEOD-52990 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Colo-205 and RKO colon adenocarcinoma cell lines treated with Novel 2-Acetamido, 6-Carboxamide Substituted Benzothiazole Derivatives as Potential BRAFV600E Inhibitors and PLX4720
Two human colorectal adenocarcinoma cell lines (Colo-205 and RKO) were treated with PLX4720 and newly synthesized 2-Acetamido, 6-Carboxamide Substituted Benzothiazole Derivatives, as potential BRAF V600E inhibitors; IDK142, IDK145, IDK133 and DMSO as control.
ORGANISM(S): Homo sapiens 
2023-12-19 | E-MTAB-13097 | biostudies-arrayexpress
GenomicsChIP-seq of MYST acetyltransferases in RKO cell line
Genome-wide mapping of MYST acetyltransferase subunit BRPF3 in RKO synchronised cells. Genome-wide mapping of MYST acetyltransferase subunit BRPF3 in RKO synchronised cells.
ORGANISM(S): Homo sapiens 
2016-02-05 | E-GEOD-63722 | biostudies-arrayexpress
TranscriptomicsGene expression data for mock and 5-Aza-CdR treated colorectal cancer (CRC) cell lines SW480, HCT116 and RKO
DNA hypermethylated genes undergo silencing and show re-expression in response to 5-Aza-CdR treatment. Agilent arrays were used to determine the genes that get reactivated in response to the drug treatment. To determine expression levels of genes in SW480, HCT116 and RKO.
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-50510 | biostudies-arrayexpress
ProteomicsRKO digested using trypsin, chemotrypsin and AspN
RKO cell pellets were digested with trypsin, chymotrypsin and AspN, respectively.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-06-22 | MSV000081188 | MassIVE
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