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Cells have evolved multiple strategies to survive environmental stress conditions. This includes the formation of membrane-less cytoplasmic ribonucleoprotein structures called stress granules that sequester and protect mRNAs encoding many housekeeping genes. Stress granules are not static biomolecul...
2026-06-16 | MTBLS13923 | MetaboLights
P granules are germ-cell-specific cytoplasmic structures containing RNA and protein and required for proper germ cell development in C. elegans. A new P-granule-associated protein, DEPS-1, whose loss disrupts P granule structure and function was analysed in this study. Genome wide analysis of gene...
ORGANISM(S): Caenorhabditis elegans 
When stress strikes, cells incur damages and initiate adaptive responses, including perturbation of RNA splicing, modulation of nuclear RNA export, and formation of stress granules. Despite their central role, knowledge of the composition and mechanisms governing stress granules in fungi remains sca...
ORGANISM(S): Fusarium graminearum 
2026-09-14 | PXD080458 | Pride
P granules in C. elegans are required for fertility and function to maintain germ cell identity and pluripotency.  Sterility in the absence of P granules is often accompanied by the mis-expression of soma-specific proteins and the initiation of somatic differentiation in germ cells.  To investigate ...
ORGANISM(S): Caenorhabditis elegans 
All cells and organisms exhibit stress-coping mechanisms to ensure survival. Cytoplasmic protein-RNA assemblies termed stress granules are increasingly recognized to promote cellular survival under stress. Thus, they might represent tumor vulnerabilities that are currently poorly explored. The trans...
2024-09-26 | MODEL2001030002 | BioModels
All cells and organisms exhibit stress-coping mechanisms toensure survival. Cytoplasmic protein-RNA assemblies termedstress granules are increasingly recognized to promote cellularsurvival under stress. Thus, they might represent tumor vul-nerabilities that are currently poorly explored. The transla...
2024-09-02 | BIOMD0000000907 | BioModels
We performed gene-expression analysis of mouse cerebellar granule cell layer as compared to that of Purkinje cells. DNA microarray analysis detected genes in cerebellar granule cell layer, most of which are classified into functional molecule categories. Our comparative analysis between Purkinje cel...
ORGANISM(S): Mus musculus 
This SuperSeries is composed of the following subset Series: GSE25774: Genome-wide analysis of Tdrd7 knockdown in lens epithelial-derived cell line 21EM15 GSE25775: Genome-wide analysis of 4-day old (P4) Tdrd7 null mouse lens GSE25776: Genome-wide analysis of 1 month old (P30) Tdrd7 null mouse lens ...
ORGANISM(S): Mus musculus 
This set of submissions contains the mass spectrometry files acquired using Data-Dependent Acquisition mode (DDA), which were paired with Data-Independent Acquisition mode (DIA) files (MSV000081414) for the manuscript by Ji-Young Youn et al. that describes the high-density proximity mapping of RNA b...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-17 | MSV000081947 | MassIVE
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