Sort   by:  
 Page size 
Mass spectrometry analysis of RNA enables measurement and quantification of modifications with sequence context. Since mass spectrometry sensitivity is limited by poor ionization efficiences of RNA oligonucleotides, we developed a ligation based sample preparation approach to improve ionization of R...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-09-16 | PXD076675 | Pride
High-throughput sequencing (HTS) has become a powerful tool for the detection of and sequence characterization of microRNAs (miRNA) and other small RNAs (sRNA). Unfortunately, the use of HTS data to determine the relative quantity of different miRNAs in a sample has been shown to be inconsistent wi...
ORGANISM(S): synthetic construct 
RNA Proximity Ligation to Resolve Intramolecular RNA Structures in situ
RNA ligases are present across all forms of life. While enzymatic RNA ligation between 5'-PO4 and 3'-OH termini is prevalent in viruses, fungi, and plants, such RNA ligases are yet to be identified in vertebrates. Here, using a nucleotide-based chemical probe targeting human AMPylated proteome, we h...
ORGANISM(S): Homo sapiens (Human) 
2023-01-27 | PXD038132 | Pride
RNA-DNA interactome of a prokaryotic cell uncovered by proximity ligation
Sort   by:  
 Page size