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ModelsLlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case2
LlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case1 Three putative effects of the asRNAs were considered in this study: in case 1 , the binding of the asRNA to the corresponding mRNA induces degradation of the duplex. In case 2   (this model)   the binding o...
2017-05-18 | MODEL1511170001 | BioModels
ModelsLlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case1
LlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case1 Three putative effects of the asRNAs were considered in this study: in case 1  (this model) , the binding of the asRNA to the corresponding mRNA induces degradation of the duplex. In case 2, the binding of the ...
2017-05-18 | MODEL1511170000 | BioModels
ModelsLlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case3
LlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case3 Three putative effects of the asRNAs were considered in this study: in case 1, the binding of the asRNA to the corresponding mRNA induces degradation of the duplex. In case 2, the binding of the asRNA to...
2017-05-18 | MODEL1511170002 | BioModels
ProteomicsTumour mutations in long noncoding RNAs enhance cell fitness
Tumour DNA contains thousands of somatic single nucleotide variants (SNVs) in non-protein-coding elements, yet their functional significance remains poorly understood. Amongst the most highly mutated elements are long noncoding RNAs (lncRNAs), functional transcripts with known roles in carcinogenesi...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD034007 | Pride
Driver gene  cancer  long non-coding rnas 
TranscriptomicsThe expression of small RNAs after prg-1 mutation
Piwi-related Argonaute proteins play important roles in maintaining germline integrity and fertility and have been linked to a class of germline-enriched small RNAs termed piRNAs. Caenorhabditis elegans encodes two Piwi family proteins called PRG-1 and PRG-2, and PRG-1 interacts with the C. elegans ...
ORGANISM(S): Caenorhabditis elegans 
2014-06-09 | E-GEOD-56272 | biostudies-arrayexpress
TranscriptomicsHigh throughput sequencing of endogenous small RNAs from AGO pathway mutants
High-throughput pyrosequencing of endogenous small RNAs from >95% male enriched populations of alg-3(tm1155);alg-4(ok1041);fog-2(q71) and fog-2(q71) worms as well as purified spermatids from fem-3(q20) adult worms. Gametogenesis is thermosensitive in numerous metazoa ranging from worms to man. In C...
ORGANISM(S): Caenorhabditis elegans 
2010-02-24 | E-GEOD-18729 | biostudies-arrayexpress
ProteomicsCD47 interactions with exportin-1 regulate targeting of m7G-capped RNAs to extracellular vesicles
CD47 is a marker of self and a signaling receptor for thrombospondin-1 that is also a membrane component of extracellular vesicles (EVs) released by various cell types. Previous studies identified CD47-dependent functional effects of EVs on target cells, mediated by delivery of their RNA contents, a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-01 | MSV000086969 | MassIVE
ProteomicsBacterial antisense RNAs are mainly the product of transcriptional noise
Cis-encoded antisense RNAs (asRNAs) are widespread along bacterial transcriptomes. However, the role of the vast majority of these RNAs remains unknown, and there is an ongoing discussion as to what extent these transcripts are the result of transcriptional noise. We show, by comparative transcripto...
ORGANISM(S): Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
2018-10-25 | PXD003231 | Pride
Asrnas Srnas Non-coding rnas Bacteria 
TranscriptomicsDiverse pathways generate microRNA-like RNAs and Dicer-independent small interfering RNAs in fungi
A variety of small RNAs, including the Dicer-dependent miRNAs and the Dicer-independent Piwi-interacting RNAs, associate with Argonaute family proteins to regulate gene expression in diverse cellular processes. These two species of small RNA have not been found in fungi. Here, by analyzing small RN...
ORGANISM(S): Neurospora crassa 
2010-07-01 | E-GEOD-21175 | biostudies-arrayexpress
TranscriptomicsGlobal analyses of endonucleolytic cleavage in mammals reveal expanded repertoires of cleavage-inducing small RNAs and their targets
In mammals, small RNAs are important players in post-transcriptional gene regulation. While their roles in mRNA destabilization and translational repression are well appreciated, their involvement in endonucleolytic cleavage of target RNAs is poorly understood. Very few microRNAs are known to guide ...
ORGANISM(S): Homo sapiens 
2016-03-16 | E-GEOD-68253 | biostudies-arrayexpress
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