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GenomicsRNF10 as an NMDA receptor-dependent signaling protein necessary for cognitive flexibility
RNF10 as an NMDA receptor-dependent signaling protein necessary for cognitive flexibility
PRJNA1027439 | ENA
UnknownE3 ubiquitin ligase RNF10 promotes dissociation of stalled ribosomes and responds to ribosomal subunit imbalance.
Not available
S-EPMC11604940 | biostudies-literature
UnknownAn epitope encoded by uORF of RNF10 elicits a therapeutic anti-tumor immune response.
Not available
S-EPMC10654591 | biostudies-literature
TranscriptomicsRNF10 as an NMDA receptor-dependent signaling protein necessary for cognitive flexibility
Activation of synaptic N-methyl-D-aspartate receptors (NMDARs) drives the nuclear translocation of synaptonuclear messengers involved in the transcriptional program engaged in synaptic plasticity. However, the role of synaptonuclear messengers in regulating cognitive behavior has not been fully clar...
ORGANISM(S): Mus musculus 
2026-08-27 | GSE245221 | GEO
UnknownRNF10 and RIOK3 facilitate 40S ribosomal subunit degradation upon 60S biogenesis disruption or amino acid starvation.
Not available
S-EPMC12008924 | biostudies-literature
ProteomicsRNF10 and RIOK3 Facilitate 40S Ribosomal Subunit Degradation upon 60S Biogenesis Disruption or Amino Acid Starvation [Fig. 2F]
Ribosome-associated quality control (RQC) pathways target ribosomes whose progression becomes impaired during various phases of the translation cycle. Ribosome ubiquitylation is a key RQC licensing step. Previous studies identified an initiation specific RQC branch (iRQC) that is activated when tran...
ORGANISM(S): Homo sapiens (Human) 
2025-02-07 | PXD060349 | Pride
Riok3 Ribosome ubiquitylation Initiation ribosome-associated quality control (irqc) Amino acid starvation Rnf10 Ribosome biogenesis 
ProteomicsRNF10 and RIOK3 Facilitate 40S Ribosomal Subunit Degradation upon 60S Biogenesis Disruption or Amino Acid Starvation [Fig. S6B]
Ribosome-associated quality control (RQC) pathways target ribosomes whose progression becomes impaired during various phases of the translation cycle. Ribosome ubiquitylation is a key RQC licensing step. Previous studies identified an initiation specific RQC branch (iRQC) that is activated when tran...
ORGANISM(S): Homo sapiens (Human) 
2025-02-07 | PXD060299 | Pride
Riok3 Ribosome ubiquitylation Initiation ribosome-associated quality control (irqc) Amino acid starvation Rnf10 Ribosome biogenesis 
ProteomicsRNF10 and RIOK3 Facilitate 40S Ribosomal Subunit Degradation upon 60S Biogenesis Disruption or Amino Acid Starvation [Fig. 5C, S5F]
Ribosome-associated quality control (RQC) pathways target ribosomes whose progression becomes impaired during various phases of the translation cycle. Ribosome ubiquitylation is a key RQC licensing step. Previous studies identified an initiation specific RQC branch (iRQC) that is activated when tran...
ORGANISM(S): Homo sapiens (Human) 
2025-02-07 | PXD060207 | Pride
Riok3 Ribosome ubiquitylation Initiation ribosome-associated quality control (irqc) Amino acid starvation Rnf10 Ribosome biogenesis 
ProteomicsRNF10 and RIOK3 Facilitate 40S Ribosomal Subunit Degradation upon 60S Biogenesis Disruption or Amino Acid Starvation [Fig. 4D, S4D]
Ribosome-associated quality control (RQC) pathways target ribosomes whose progression becomes impaired during various phases of the translation cycle. Ribosome ubiquitylation is a key RQC licensing step. Previous studies identified an initiation specific RQC branch (iRQC) that is activated when tran...
ORGANISM(S): Homo sapiens (Human) 
2025-02-07 | PXD060334 | Pride
Riok3 Ribosome ubiquitylation Initiation ribosome-associated quality control (irqc) Amino acid starvation Rnf10 Ribosome biogenesis 
ProteomicsRNF10 and RIOK3 Facilitate 40S Ribosomal Subunit Degradation upon 60S Biogenesis Disruption or Amino Acid Starvation [Fig. S6C-D]
Ribosome-associated quality control (RQC) pathways target ribosomes whose progression becomes impaired during various phases of the translation cycle. Ribosome ubiquitylation is a key RQC licensing step. Previous studies identified an initiation specific RQC branch (iRQC) that is activated when tran...
ORGANISM(S): Homo sapiens (Human) 
2025-02-07 | PXD060294 | Pride
Riok3 Ribosome ubiquitylation Initiation ribosome-associated quality control (irqc) Amino acid starvation Rnf10 Ribosome biogenesis 
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