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ProteomicsMouse RNF138 immunoprecipitation mass spectrography analysis in macrophages
As one of the core components of the SWI/SNF complex, SMARCC1 (BAF155, SRG3) plays essential roles in activation of the late inflammatory genes in response to microbial challenge. However, little is known about the mechanism how SMARCC1 regulates the inflammatory innate response. Via functional scre...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-10 | PXD039333 | Pride
Mass spectrography analysis Mouse Macrophages Rnf138 
GenomicsRNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of SWI/SNF complex
RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of SWI/SNF complex
PRJNA855477 | ENA
UnknownRnf138 deficiency promotes apoptosis of spermatogonia in juvenile male mice.
Not available
S-EPMC5520686 | biostudies-literature
UnknownRNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway.
Not available
S-EPMC11984406 | biostudies-literature
TranscriptomicsRNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of SWI/SNF complex
As one of the core components of the SWI/SNF complex, SMARCC1 (SAF155, SRG3) plays essential role in activation of the late inflammatory genes in response to microbial challenge. However, little is known about the mechanisms how SMARCC1 is regulated in innate response. Here, we identify for the firs...
ORGANISM(S): Mus musculus 
2023-02-11 | GSE207437 | GEO
UnknownRNF138 interacts with RAD51D and is required for DNA interstrand crosslink repair and maintaining chromosome integrity.
Not available
S-EPMC4884500 | biostudies-literature
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and RNF138-/- mice colorectal transcriptomes in DSS, AOM/DSS and organoids samples
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and RNF138-/- mice colorectal transcriptomes in DSS, AOM/DSS and organoids samples
PRJNA602628 | ENA
UnknownRNF138-mediated ubiquitination of rpS3 is required for resistance of glioblastoma cells to radiation-induced apoptosis.
Not available
S-EPMC5799804 | biostudies-literature
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and RNF138-/- mice colorectal transcriptomes in DSS, AOM/DSS and organoids samples
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to analysis NGS-derived transcriptome profiling (RNA-seq) in DSS induced chronic inflammation, AOM/DSS induced colitis-associated colorectal tumorigenesis and organoi...
ORGANISM(S): Mus musculus 
2022-04-30 | GSE144051 | GEO
UnknownSystematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair.
Not available
S-EPMC4894550 | biostudies-literature
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