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ProteomicsProteomic Analysis of fly brain cytoplasmic RNP granules containing the lncRNA mimi
In neurons, mRNAs and associated RNA-binding proteins assemble into ribonucleoprotein (RNP) granules essential to regulate mRNA trafficking, local translation, and turnover. Dysregulation of RNA-protein condensation can disturb synaptic plasticity. We report that the novel lncRNA mimi is a constitut...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-10-12 | PXD034453 | Pride
Rnp granules  fly brain  neurons  lncrna mimi Fne  rbp9 Drosophila  relative ibaq  quantitative proteomics 
UnknownMulticolour single-molecule tracking of mRNA interactions with RNP granules.
Not available
S-EPMC6375083 | biostudies-literature
GenomicsRNP granule enrichment from Trypanosoma brucei
Novel insights into RNP granules by employing the trypanosome’s microtubule skeleton as a molecular sieve
PRJEB8187 | ENA
UnknownPromiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules.
Not available
S-EPMC4522596 | biostudies-literature
ProteomicsDifferential assembly of RNP granules via activation of distinct dsRNA sensors by adenovirus mutants
Recognition of dsRNA triggers antiviral defense mediated by PKR and OAS3/RNase L pathways through translational arrest and RNA decay. This is accompanied by assembly of distinct cytoplasmic ribonucleoprotein (RNP) condensates termed stress granules (SGs) and RNase L-dependent bodies (RLBs). Here we ...
ORGANISM(S): Homo sapiens (Human) 
2026-07-10 | PXD075408 | Pride
Dna viruses Rnase l-dependent bodies (rlbs) Adenovirus 5 (ad5) Stress granules (sgs) 
UnknownRNA is required for the integrity of multiple nuclear and cytoplasmic membrane-less RNP granules.
Not available
S-EPMC9058542 | biostudies-literature
UnknownRNAi Screen Identifies Novel Regulators of RNP Granules in the Caenorhabditis elegans Germ Line.
Not available
S-EPMC4978917 | biostudies-literature
UnknownNovel insights into RNP granules by employing the trypanosome's microtubule skeleton as a molecular sieve.
Not available
S-EPMC4652759 | biostudies-literature
ProteomicsThe Proteome and Transcriptome of Stress Granules and P-Bodies during Human T Lymphocytes Activation
Stress granules (SGs) and processing bodies (PBs) are membraneless cytoplasmic assemblies regulating mRNAs under environmental stress such as viral infections, neurological disorders, or cancer. Upon antigen stimulation, T lymphocytes mediate their immune functions under regulatory mechanisms involv...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD031639 | Pride
Human t lymphocytes Ribonucleoprotein granules Proteome 
UnknownAmyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons.
Not available
S-EPMC5373408 | biostudies-literature
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