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This dataset has been designed to test whether codons in mRNAs and anticodons in tRNAs vary in order to maximize translation in specific cellular conditions in mammals. Prokaryotes and simple unicellular eukaryotes optimize their translational rates by adjusting the codons in the protein-coding tran...
ORGANISM(S): human 
This dataset has been designed to test whether codons in mRNAs and anticodons in tRNAs vary in order to maximize translation in specific cellular conditions in mammals. Prokaryotes and simple unicellular eukaryotes optimize their translational rates by adjusting the codons in the protein-coding tran...
ORGANISM(S): human 
Homologous vertebrate tissues express a highly conserved set of transcribed genes; paradoxically, expression of tRNAs that are required to translate mRNAs into proteins have been reported to be divergent. To resolve this paradox, we mapped the genome-wide occupancy of pol III in primary tissues iso...
ORGANISM(S): Mus musculus 
We assessed the impact of leaving a lyophilized mixture consisting of 125 peptides at room temperature for up to 20 days, and we assessed the effect on the quantitative performance of multiple reaction monitoring-MS (MRM-MS) assays. The findings suggest that there are no significant differences in t...
ORGANISM(S): Homo Sapiens 
2022-09-05 | PXD028179 | panorama
We conducted a genome wide survey of mosquito gene expression profiles during 8 different time periods of the Anopheles gambiae lifecycle. The timeperiods included embryos, E, collected 12-14 hours post oviposition (hpo), five larval samples, La-Le, with La collected approximately 48h hpo and the re...
ORGANISM(S): Anopheles gambiae 
We recently identified the DNA repair complex XPC-RAD23B-CETN2 as a stem cell coactivator (SCC) required for OCT4 and SOX2 transcriptional activation. Here we investigate genome-wide the role of SCC in murine ESCs by mapping regions bound by its RAD23B subunit in wild type and Xpc-/- ESCs, and analy...
ORGANISM(S): Mus musculus 
Early B cell development is orchestrated by the combined activities of the transcriptional regulators E2A, EBF1, Foxo1 and Ikaros. However, how the genome-wide binding patterns of these regulators are modulated during B-lineage development remains to be determined. Here, we found that in lymphoid pr...
ORGANISM(S): Mus musculus 
We conducted a genome wide survey of mosquito gene expression profiles in 4 different tissues of adult Anopheles gambiae mosquitoes. The tissues included the head, the midgut, the carcass (corresponding to the remainder of the mosquito after decapitation and midgut removal) and ovaries. Ovaries were...
ORGANISM(S): Anopheles gambiae 
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