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TranscriptomicsA general framework for optimization of probes for gene expression microarray and its application to the fungus Podospora anserina
A genome wide microarray, covering the 10546 presently known and predicted CDS, has been constructed with the Agilent in-situ synthesized 60-mers technology. 1) A library of 10 oligonucleotides per CDS has been design by the manufacturer. 2) A computational step has been performed to determine 3' po...
ORGANISM(S): Podospora anserina 
2010-06-30 | E-GEOD-20734 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of individual human oocytes and embryos
Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals. Data from assisted reproduction programmes provides additional evidence that this is largely mediated at the level of embryonic ...
ORGANISM(S): Homo sapiens 
2013-12-13 | E-MEXP-3870 | biostudies-arrayexpress
UnknownPhase I multidose-escalation study of the anti-CD19 maytansinoid immunoconjugate SAR3419 administered by intravenous infusion every 3 weeks to patients with relapsed/refractory B-cell lymphoma.
Not available
S-EPMC5950497 | biostudies-literature
TranscriptomicsZebularine effect on mouse embryonic stem cells manifested as cardiod-myogenic potential: testable hypothesis generation using microarray data
Lineage commitment during Embryonic Stem Cells (ESCs) differentiation is controlled not only by a gamut of transcription factors but also by epigenetic events, mainly histone deacetylation and promoter DNA methylation. Moreover, the DNA demethylation agent 5′-Aza-2′-deoxycytidine (AzadC) has been wi...
ORGANISM(S): Mus musculus 
2011-05-05 | E-GEOD-29072 | biostudies-arrayexpress
TranscriptomicsGenome-wide gene expression profiling of fertilization competent mycelium in opposite mating types in the heterothallic fungus Podospora anserina.
Abstract BACKGROUND: Mating-type loci in yeasts and ascomycotan filamentous fungi (Pezizomycotina) encode master transcriptional factors that play a critical role in sexual development. Genome-wide analyses of mating-type-specification circuits and mating-type target genes are available in Saccharo...
ORGANISM(S): Podospora anserina 
2011-12-22 | E-GEOD-27297 | biostudies-arrayexpress
TranscriptomicseIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies
The amounts of eIF4G and eIF4B were decreased in the vemurafenib-treated sensitive A375 cell line. To find mechanisms behind this decrease, we sought to identify the genes whose expression changes after vemurafenib treatment in A375 cells as compared to Mel624 cells by using microarrays.
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2607 | biostudies-arrayexpress
TranscriptomicsGW4064 treatment on GLUTag cells
To identify genes regulated by FXR in GLUTag cell line, we compared gene expression profiles in GLUTag cells treated for 24h by 0.1% DMSO and by 5M-5M GW4064
ORGANISM(S): Mus musculus 
2015-06-21 | E-MTAB-2199 | biostudies-arrayexpress
UnknownCase series of intestinal microsporidiosis in non-HIV patients caused by Encephalitozoon hellem.
Not available
S-EPMC10543343 | biostudies-literature
UnknownEpidemiology of perioperative anaphylaxis in France in 2017-2018: the 11th GERAP survey.
Not available
S-EPMC11130666 | biostudies-literature
UnknownLow HDL-Cholesterol Concentrations in Lung Transplant Candidates are Strongly Associated With One-Year Mortality After Lung Transplantation.
Not available
S-EPMC9884674 | biostudies-literature
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