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TranscriptomicsDifferential expression associated with GB virus C in HCV/HIV co-infection
The aim of this study was to identify differential gene and protein expression associated with GBV-C that may be of importance in reduction of HCV-related liver disease. GB virus C (GBV-C) infection leads to improved outcomes in human immunodeficiency virus (HIV) infection. Furthermore, GBV-C has be...
ORGANISM(S): Homo sapiens 
2011-05-10 | E-GEOD-16593 | biostudies-arrayexpress
MetabolomicsA metabolic dependency for host isoprenoids in the obligate intracellular pathogen Rickettsia parkeri underlies a sensitivity for the statin class of host-targeted therapeutics
Gram-negative bacteria in the order Rickettsiales are obligate intracellular parasites that cause human diseases such typhus and spotted fever. They have evolved a dependence on essential nutrients and metabolites from the host cell as a consequence of extensive genome streamlining. However, it rema...
2019-10-31 | MTBLS846 | MetaboLights
MetabolomicsTreatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics
Introduction: Obestatin is a controversial gastrointestinal peptide purported to have metabolic actions. Objectives: This study investigated whether treatment with a stable obestatin analogue (PEG-OB(Cys10, Cys13) changed plasma metabolite levels firstly in lean and subsequently in diet-induced obes...
2017-07-25 | MTBLS334 | MetaboLights
Unknown3D-FISH analysis reveals chromatid cohesion defect during interphase in Roberts syndrome.
Not available
S-EPMC4197286 | biostudies-literature
UnknownControlled Substance Lock-In Programs: Examining An Unintended Consequence Of A Prescription Drug Abuse Policy.
Not available
S-EPMC7262687 | biostudies-literature
UnknownNovel Primate Model of Serotonin Transporter Genetic Polymorphisms Associated with Gene Expression, Anxiety and Sensitivity to Antidepressants.
Not available
S-EPMC4946067 | biostudies-literature
TranscriptomicsA mutation in a splicing factor that causes retinitis pigmentosa (RP) has a transcriptome-wide effect on mRNA splicing
Background: Substantial progress has been made in the identification of sequence elements that control mRNA splicing and the genetic variants in these elements that alter mRNA splicing (referred to as splicing quantitative trait loci -- sQTLs). Genetic variants that affect mRNA splicing in trans are...
ORGANISM(S): Homo sapiens 
2012-12-25 | E-GEOD-43134 | biostudies-arrayexpress
UnknownImproved Health Outcomes from Hepatitis C Treatment Scale-Up in Spain's Prisons: A Cost-Effectiveness Study.
Not available
S-EPMC6856347 | biostudies-literature
ProteomicsSex specific disruptions in PKCγ signaling in a mouse model of Spinocerebellar Ataxia Type 14
Spinocerebellar Ataxia Type 14 (SCA14) is an autosomal dominant neurodegenerative disease caused by mutations in the gene-encoding protein kinase C gamma (PKCγ), a Ca2+/diacylglycerol (DG)-dependent serine/threonine kinase dominantly expressed in the Purkinje cells of the cerebellum, a brain region ...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-16 | PXD060630 | Pride
Phosphoproteome Mouse Pkc Phosphorylation 
UnknownContributions of replicative and translesion DNA polymerases to mutagenic bypass of canonical and atypical UV photoproducts.
Not available
S-EPMC10160025 | biostudies-literature
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