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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
ModelsRoberts2010 - Genome-scale metabolic network of Clostridium thermocellum (iSR432)
Roberts2010 - Genome-scale metabolic network of Clostridium thermocellum (iSR432) This model is described in the article: Genome-scale metabolic analysis of Clostridium thermocellum for bioethanol production. Roberts SB, Gowen CM, Brooks JP, Fong SS. BMC Syst Biol 2010; 4:...
2015-07-30 | MODEL1507180004 | BioModels
TranscriptomicsMycobacterium tuberculosis efpA CRISPRi knock-down transcriptional profile - induced efpA knock-down strain vs non-induced condition
In Mycobacterium tuberculosis, the efflux pump, EfpA, plays an essential but uncharacterised role in its physiology and antibiotic tolerance. In this study, an ATc-inducible CRISPR interference (CRISPRi) system was introduced into M. tuberculosis to knock-down the expression of efpA and determine an...
ORGANISM(S): Mycobacterium tuberculosis 
2024-06-19 | E-MTAB-13755 | biostudies-arrayexpress
GenomicsTDP-1, the C. elegans ortholog of TDP-43, limits the accumulation of double stranded RNA
C. elegans mutants deleted for TDP-1, an ortholog of the neurodegeneration-associated RNA binding protein TDP-43, display only mild phenotypes. Nevertheless, transcriptome sequencing revealed that many RNAs were altered in accumulation and/or processing in the mutant. Analysis of these transcription...
ORGANISM(S): Caenorhabditis elegans 
2014-11-19 | E-GEOD-61581 | biostudies-arrayexpress
no omics definedChromatin immunoprecipitation with anti-human-cMyc antibody of yeast grown in 0.03% MMS for 0, 15 and 60 minutes
Cells were grown with 0.03% MMS and samples collected before adding MMS, 15 and 60 minutes after adding MMS.
ORGANISM(S): Saccharomyces cerevisiae 
2006-11-16 | E-MEXP-905 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast grown in media with and without amino acids
Effect of Amino Acid Starvation on Ino4 Binding. Comparing SCD conditions to 4hrs of Amino Acid starvation
ORGANISM(S): Saccharomyces cerevisiae 
2006-11-16 | E-MEXP-906 | biostudies-arrayexpress
UnknownNK cell survival mediated through the regulatory synapse with human DCs requires IL-15Ralpha.
Not available
S-EPMC2030458 | biostudies-literature
UnknownBroadened and elevated humoral immune response to EBNA1 in pediatric multiple sclerosis.
Not available
S-EPMC2676958 | biostudies-literature
ProteomicsSkeletal muscle proteome changes following 10 weeks of high load resistance training
Recreationally-trained college aged males underwent 10 weeks of moderate volume, high-load resistance exercise with PRE and POST vastus lateralis skeletal muscle biopsies. Protein isolation was performed on tissue samples and the sarcoplasmic protein fraction was analyzed to evaluate changes PRE to...
ORGANISM(S): Homo sapiens (Human) 
2020-03-26 | PXD017805 | Pride
Human 
UnknownImpact of Scala Tympani Geometry on Insertion Forces during Implantation.
Not available
S-EPMC9688204 | biostudies-literature
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