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TranscriptomicsGain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with adverse clinical outcome
This SuperSeries is composed of the following subset Series: GSE27331: Gain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with adverse clinical outcome [penn1Mb data] GSE27332: Gain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with a...
ORGANISM(S): Homo sapiens 
2011-02-16 | E-GEOD-27333 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Cornelia de Lange Syndrome proband derived cell lines reveals defective cohesin in cdls mediates gene expression with characteristics of transcription factor and insulator activity
The Cohesin apparatus has a canonical role in sister chromatid cohesion. Heterozygous mutations in Nipped B-like (NIPBL), SMC1A, and SMC3 have been found in 60% of probands with Cornelia de Lange Syndrome (CdLS), a dominant multi-system genetic disorder with variable expression. We have performed a ...
ORGANISM(S): Homo sapiens 
2009-06-08 | E-GEOD-12408 | biostudies-arrayexpress
GenomicsGenome-Wide Analysis of Hypodiploid Acute Lymphoblastic Leukemia

Hypodiploid acute lymphoblastic leukemia (ALL) is an aggressive form of leukemia characterized by multiple whole chromosomal losses and very poor outcome. Here we report an integrative genomic analysis that identifies multiple subtypes of hypodiploid ALL characterized by variation in the degree o...

phs000341.v1.p1 | EGA
TranscriptomicsGain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with adverse clinical outcome [camb1Mb data]
For many oncogenes, increased expression resulting from copy number gain confers a selective advantage to cells that consequently make up the tumour bulk. To identify oncogenes of potential biological significance in cervical squamous cell carcinoma (SCC), 36 primary samples and ten cell lines were ...
ORGANISM(S): Homo sapiens 
2011-02-16 | E-GEOD-27332 | biostudies-arrayexpress
TranscriptomicsGain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with adverse clinical outcome [penn1Mb data]
For many oncogenes, increased expression resulting from copy number gain confers a selective advantage to cells that consequently make up the tumour bulk. To identify oncogenes of potential biological significance in cervical squamous cell carcinoma (SCC), 36 primary samples and ten cell lines were ...
ORGANISM(S): Homo sapiens 
2011-02-16 | E-GEOD-27331 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila cell lines S3, Kc and S3
Background: We would like to use Drosophila cell lines to investigate the transcriptional responses to Nitric Oxide donors and inhibitors. As a pilot to this we would like to compare the transcriptional profile of 3 cell lines we are using in our lab (S3, Kc and S3). This study is being done in para...
ORGANISM(S): Drosophila melanogaster 
2004-05-07 | E-FLYC-4 | biostudies-arrayexpress
TranscriptomicsFunctional evidence that Drosha over-expression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles [mRNA]
Comparison of mRNA expression profiles in W12 Series 1 cervical ectokeratinocytes at passage number 22 versus 19 (during which time the cells gain an invasive phenotype) As these cells demonstrate gain of chromosome 5p during this time, mRNA expression profiling data interrogated for over-expressed ...
ORGANISM(S): Homo sapiens 
2011-05-25 | E-GEOD-26176 | biostudies-arrayexpress
TranscriptomicsGene expression analysis in a variety of normal, premalignant and squamous cell carcinomas of the cervix
We sought to apply the technologies of gene expression profiling to detect genes significant in the aetiology of cervical carcinoma . We investigated 14 normal (NAD), 11 low grade squamous intrapepithelial lesions (LSIL), 21 high grade squamous intraepithelial lesions (HSIL) and 28 squamous cell ca...
ORGANISM(S): Homo sapiens 
2013-09-17 | E-GEOD-27678 | biostudies-arrayexpress
TranscriptomicsAn integrated genomics approach for novel biomarker discovery in squamous cell cervical carcinoma
Detection of copy number dependent gene expression profiles in epithelial tumours has lead to the discovery of genes significant in diagnosis, prognosis and of therapeutic value. We sought to apply the technologies of gene expression profiling and copy number aberration detection by high density oli...
ORGANISM(S): Homo sapiens 
2011-03-05 | E-GEOD-27673 | biostudies-arrayexpress
UnknownReplication and trafficking of a plant virus are coupled at the entrances of plasmodesmata
Not available
S-JCBD-201304003 | bioimages
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