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TranscriptomicsScleroderma and Gleevec treatment
Total RNA was extracted from skin biopsies before and after imatinib (Gleevec) treatment using Qiagen RNeasy fibrous tissue kit. RNA was amplified using the Ambion Amino Allyl MessageAmp II aRNA kit. Amplified skin RNA (labeled with Cy5) and amplified Stratagene Human Universal Reference RNA (labele...
ORGANISM(S): Homo sapiens 
2009-03-31 | E-GEOD-11130 | biostudies-arrayexpress
UnknownTumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE.
Not available
S-EPMC3272371 | biostudies-literature
TranscriptomicsGlobal Analysis of the Immediate Transcriptional Effects of Estrogen Signaling Reveals a Rapid, Extensive, and Transient Response
We report the immediate effects of estrogen signaling on the transcriptome of breast cancer cells using Global Run-On and sequencing (GRO-seq). We found that estrogen signaling directly regulates a strikingly large fraction of the transcriptome in a rapid, robust, and unexpectedly transient manner. ...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-27463 | biostudies-arrayexpress
TranscriptomicsDefining the Roles and Regulation of the GATA-factor ELT-2 in the C. elegans Endoderm
We identified genome-wide sites of occupancy for the intestine-specific transcription factor ELT-2 in L3-staged N2 worm by performing ELT-2 ChIP-seq on whole worms; we performed RNA-seq on L3-staged N2 whole worms To identify DNA regions of direct ELT-2 occupancy, we performed the following ChIP-seq...
ORGANISM(S): Caenorhabditis elegans 
2016-03-30 | E-GEOD-71720 | biostudies-arrayexpress
ProteomicsUnraveling Oxidative Stress Resistance: Molecular Properties Govern Proteome Vulnerability
Oxidative stress leads to damage of protein molecules, particularly accumulation of protein carbonyls. Deleterious effects of protein carbonylation by reactive oxygen species (ROS) make understanding molecular properties determining ROS-susceptibility essential. The radiation-resistant bacterium Dei...
ORGANISM(S): Deinococcus Radiodurans R1 Escherichia Coli 
2020-10-22 | PXD020058 |
UnknownA Qualitative Evaluation Exploring Co-Production of Falls Management in Care Homes.
Not available
S-EPMC12630552 | biostudies-literature
UnknownChanges in matrix protein biochemistry and the expression of mRNA encoding matrix proteins and metalloproteinases in posterior tibialis tendinopathy.
Not available
S-EPMC3329235 | biostudies-literature
UnknownProtein secondary structure determines the temporal relationship between folding and disulfide formation.
Not available
S-EPMC7039548 | biostudies-literature
UnknownParent perceptions and decision making about treatments for epilepsy: a qualitative evidence synthesis.
Not available
S-EPMC9890834 | biostudies-literature
UnknownImpact of Intensity-Modulated Radiation Therapy Technique for Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial.
Not available
S-EPMC5455690 | biostudies-literature
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