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UnknownCorrelative Analysis of Genetic Alterations and Everolimus Benefit in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Results From BOLERO-2.
Not available
S-EPMC5070556 | biostudies-literature
TranscriptomicsA grapevine anthocyanin acyltransferase, transcriptionally regulated by VvMYBA, can produce most acylated anthocyanins present in grape skins
Anthocyanins are flavonoid compounds responsible for red/purple colours in the leaves, fruit and flowers of many plant species. They are produced through a multistep pathway which is controlled by MYB transcription factors. VvMYBA1 and VvMYBA2 activate anthocyanin biosynthesis in grapevine (Vitis vi...
ORGANISM(S): Vitis vinifera 
2015-10-16 | E-GEOD-56915 | biostudies-arrayexpress
UnknownMolecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma.
Not available
S-EPMC6369924 | biostudies-literature
TranscriptomicsPemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma
We devised a high-throughput, cell-based assay to identify novel therapeutic compounds to treat Group3 medulloblastoma (G3 MB). Mouse G3 MBs, grown as neurospheres, were screened against a library of approximately 7,000 compounds including FDA-approved drugs. We identified two FDA-approved drugs, ...
ORGANISM(S): Mus musculus 
2014-04-15 | E-GEOD-46406 | biostudies-arrayexpress
UnknownResponses of the putative trachoma vector, Musca sorbens, to volatile semiochemicals from human faeces.
Not available
S-EPMC7069642 | biostudies-literature
TranscriptomicsTranscription profiling of honeey bee to assess the effects of mating and instrumental insemination on honey bee behavior physiology and brain gene expression
Mating is fundamental to the success and reproduction of most organisms, although the physiological and transcriptional changes associated with this process have been largely characterized only in Drosophila. In this study, we use honey bees as a model system since their queens undergo massive and ...
ORGANISM(S): Apis mellifera 
2009-12-01 | E-MEXP-2205 | biostudies-arrayexpress
UnknownRandomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers.
Not available
S-EPMC10497190 | biostudies-literature
GenomicUse of WGS for Diagnosis and Discovery in the Cancer Genetics Clinic

Despite the potential of whole-genome sequencing (WGS) to improve patient diagnosis and care, the empirical value of WGS in the cancer genetics clinic is unknown. We performed WGS on members of two cohorts of cancer genetics patients: those with BRCA1/2 mutations (n = 176) and those without (n = ...

phs000942 | dbGaP
UnknownA Phase I First-in-Human Study of ABBV-011, a Seizure-Related Homolog Protein 6-Targeting Antibody-Drug Conjugate, in Patients with Small Cell Lung Cancer.
Not available
S-EPMC11565168 | biostudies-literature
Genomics4dbf9af0-d667-494b-b3d9-c80c112d0527 - samples
high depth WGS sequencing of 8 sites of a RET fusion tumour
EGAD00001006878 | EGA
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