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TranscriptomicsDual knockdown of Esrrb and Sox2 in mouse embryonic stem cells
Esrrb, Sox2 or Esrrb and Sox2 were knocked down in mouse ES cells using shRNA plasmid pSUPER.puro containing shRNAs from the publications Feng et al., 2009 and Rodda et al., 2005. Knockdown was transfected into mouse ES cells using lipofectamine and then cells were selected for knockdown using purom...
ORGANISM(S): Mus musculus 
2012-11-22 | E-GEOD-34170 | biostudies-arrayexpress
TranscriptomicsIdentification of Oct4-dependent genes in vivo
Transcriptome analysis of Oct4 null and wild type preimplantation mouse embryos by RNA-sequencing N=3 embryos of two genotypes (+/+ or -/-) at each of three time points (E2.5, E3.75, E4.5) were sequenced.
ORGANISM(S): Mus musculus 
2013-06-06 | E-GEOD-47089 | biostudies-arrayexpress
UnknownInvestigating the potential of Zernike polynomials to characterise spatial distribution of macular pigment.
Not available
S-EPMC6534297 | biostudies-literature
TranscriptomicsTranscriptional profiling of 7SK knockdown in mouse embryonic stem cells
Transcriptome profiling of mouse embryonic stem cells following antisense knockdown of the non-coding RNA 7SK.
ORGANISM(S): Mus musculus 
2013-09-09 | E-MTAB-1585 | biostudies-arrayexpress
UnknownOncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival.
Not available
S-EPMC4015761 | biostudies-literature
TranscriptomicsScreening a large, ethnically diverse population of human embryonic stem cells identifies a chromosome 20 minimal amplicon that confers a growth advantage
The International Stem Cell Initiative analyzed 127 human embryonic stem cell lines and 11 induced pluripotent cell lines, from 39 laboratories worldwide for genetic changes occurring during culture. Most cell lines were analyzed at an early and late passage. Population structure analysis from SNP...
ORGANISM(S): Homo sapiens 
2011-11-12 | E-GEOD-33522 | biostudies-arrayexpress
TranscriptomicsSingle-Cell RNA-seq Defines the Three Cell Lineages of the Human Blastocyst
Despite morphological similarities, relatively little is known about conserved developmental processes in human and mouse pre-implantation embryos. Here we provide the first comprehensive single-cell RNA-sequencing comparison of human and mouse embryos from the zygotic to the blastocyst stage. We...
ORGANISM(S): Homo sapiens 
2015-08-26 | E-GEOD-66507 | biostudies-arrayexpress
UnknownPhosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis.
Not available
S-EPMC4524121 | biostudies-literature
UnknownA Review of Prostate Organogenesis and a Role for iPSC-Derived Prostate Organoids to Study Prostate Development and Disease.
Not available
S-EPMC8658468 | biostudies-literature
UnknownNatural Exposure- and Vaccination-Induced Profiles of Ex Vivo Whole Blood Cytokine Responses to Coxiella burnetii.
Not available
S-EPMC9259895 | biostudies-literature
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